Anisole, also called anisole, is a kind of aromatic ether, and its molecular formula is C6H5OCH3. Colorless liquid with fragrance. It is soluble in ethanol and ether, but insoluble in water. Anisole is prone to electrophilic substitution reaction on the aromatic ring. The reaction with phosphorus pentachloride mainly produces p-chloroanisole and a small amount of o-chloro products; the reaction with sulfuryl chloride produces 2,4,6-trichloroanisole. In addition, when anisole is heated with hydrobromic acid or hydroiodic acid, the carbon-oxygen bond is broken to produce phenol and halogenated methane, which is an important method for determining the methoxy group on the benzene ring. Anisole was originally obtained from distilled methyl salicylate or methoxybenzoic acid. Today, it is mainly prepared by reacting methylating reagent dimethyl sulfate with phenol in an alkaline aqueous solution. Can be used as organic synthetic materials, such as synthetic resins, perfumes, etc.
Manufacturing
