Aprepitant

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Aprepitant

CAS NO.： 170729-80-3

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Packing： 25KG/Fibre Drum

Product Detail

Properties

English Name :Aprepitant

CAS# :170729-80-3

Aprepitant

CAS # 170729-80-3

US-DMF No. 28866

Alias 5- [2 (R)-[1 (R)-[3,5-bis (trifluoromethyl) phenyl] ethoxy] -3 (S)-(4-fluorophenyl) morpholine- 4-ylmethyl] -3,4-dihydro-2H-1,2,4-triazol-3-one

Catalog number AP0600

CAS # 170729-80-3

Molecular formula C23H21F7N4O3

Molecular weight 534.43

Product introduction

CAS 170729-80-3

US-DMF No. 28866 Aprepitant, English name Aprepitant

Aprepitant is used to treat depression and chemotherapyinduced vomiting. It can prevent acute and delayed nausea and vomiting caused by the first and subsequent repeated chemotherapy.

Properties

Arepitan is a neurokinin-1 (NK-1) receptor blocker, which blocks the action of substance P by binding with NK-1 receptor (mainly in the central nervous system and its periphery). It is mainly used to treat nausea and vomiting induced by chemotherapy.

CAS No.

170729-80-3

Formula

C23H21F7N4O3

Molecular Mass

534.42700

Exact Mass

534.15000

PSA

83.24000

Logp

4.89000