Telmisartan

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Telmisartan

CAS NO.： 144701-48-4

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Specification： USP/CP

Documentation：

COA

Lead Time： 14-30 days

Max Capacity： 10.5MT/Year

Packing： 15KG/Fibre Drum

Product Detail

Properties

Telmisartan

Product name	Telmisartan
CAS	144701-48-4
Molecular formula	C₃₃H₃₀N₄O₂
Molecular mass	514.62
Structural formula
Appearance	White to off-white crystalline powder
Purity	99%
Certification	GMP
Raw material grade	Pharmaceutical grade
Storage	Sealed storage
Packaging	Packed in double medical polyethylene bag, 15 kg/barrel

Properties

Telmisartan is a new type of antihypertensive drug, which is a specific angiotensin II receptor antagonist for the treatment of essential hypertension. The substitution of angiotensin Ⅱ receptor for at Ⅰ receptor subtype has high affinity binding. Telmisartan has no agonist effect at the at I receptor site, but selectively binds to at I receptor, which is persistent. It has no affinity for other receptors. The function of other receptors mentioned above is unknown, and the possible receptor hyperstimulation effect caused by telmisartan is also unknown. Telmisartan did not inhibit plasma renin or block ion channels. It did not inhibit angiotensin converting enzyme II, which could also degrade bradykinin induced adverse reactions.

CAS No.

144701-48-4

Formula

C33H30N4O2

Molecular Mass

514.61700

Exact Mass

514.23700

PSA

72.94000

Logp

7.26440