(2E)-2-[(4R)-4-(2,4-Dichlorophenyl)-1,3-Dithiolan-2-Ylidene]-2-Imidazol-1-Ylacetonitrile

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CAS NO.： 187164-19-8

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Specification： 99.0%

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Product Detail

Properties

English Name :Luliconazole

CAS# :187164-19-8

Luliconazole

CAS 187164-19-8

US-DMF No. 28409

Alias 4- (2,4-dichlorophenyl) -1,3-dithiopentane-2-idene-1-imidazolylacetonitrile

Catalog number AP0400

CAS # 187164-19-8

Molecular formula C14H9Cl2N3S2

Molecular weight 354.28

Product introduction

Luliconazole, the English name is Luliconazole

Luliconazole is an imidazole antifungal drug developed by Japan Pesticide Corporation. The drug was finally approved in June 2005. It has been marketed under the trade name Lulicon since July 20, 2005. The cream and lotion specifications are both 1% and are used for the following fungal infections: ringworm-athlete's foot, ringworm, Tinea cruris; Candida infection-interphalangeal erosion, abrasion; Vitiligo.

Properties

Luriconazole is a new imidazole topical antifungal drug. It is a lanoconazole analogue. It interferes with the synthesis of fungal cell wall and fungal growth by inhibiting the activity of wool sterol demethylase and reducing the level of ergosterol. In addition to the treatment of tinea pedis, tinea cruris and tinea corporis, it has also been developed for the treatment of tinea onychomycosis (onychomycosis), and has entered phase III clinical practice.

CAS No.

187164-19-8

Formula

C14H9Cl2N3S2

Molecular Mass

354.27700

Exact Mass

352.96100

PSA

92.21000

Logp

5.06088