Ribavirin

[Chemical name]1-ß-D-Ribofuranosyl -1,2,4- t riazolc-3-Carboxamide

[Molecular formula]C₈H₁₂N₄O₅

[Molecular weight]244.21

[Use]Ribavirin is broad--spectum antivirotic drug. It is used in viral infection ofrespiratory, influenza, encephalitis B, Virus pneumonia, infant adenovirus pneumonia,

viralhepatitis, paro-titis, herpes varicellosus, herper zoster, herpes mouth, herpes genitalis, measles,viral keratitis, conjunctivitis, trachoma, rhinovirus, plasmodiai viral flat wart,psoriasis auturmn diarrhea and korin tever.

[Standard]

Description:White crystalline powder, odourless, tasteless

Specific rotation:-33.5^o～37.0^o

Loss on drying: ≤0.5%

Residue on ignition: ≤0.25%

Heavy metals: ≤10ppm

PH:4.0-6.5

Assay:98.9%~101.5%

In compliance with USP 30 and CP2005

[Storage]Preserved in tight containers from light.

Properties

Ribavirin, a guanosine and hypoxanthine nucleoside analogues, is a broad-spectrum antiviral drug, which has a good inhibitory effect on a variety of DNA and RNA viruses. It has many action sites, is not easy to produce drug resistance, high efficacy, low toxicity, small side effects and other characteristics, has been used in the treatment of a variety of viruses. It is clinically used for the treatment of hepatitis C virus, respiratory syncytial virus and Lassa fever virus infection.

CAS No.

36791-04-5

Formula

C8H12N4O5

Molecular Mass

244.20500

Exact Mass

244.08100

PSA

143.72000

Logp

-2.31120