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Introduction:
Vorolazan fumarate (tak-438), a potassium ion (K +) competitive acid blocker (p-cab), is a reversible proton pump inhibitor. After entering the human body, this product stops the secretion of gastric acid by inhibiting the combination of K + and H + - K + - ATPase (proton pump) in the last step of acid secretion in gastric parietal cells. This product has a strong and lasting effect of inhibiting gastric acid secretion.
CAS：881681-01-2
Molecular formula: C21H20FN3O6S
Molecular weight: 461.46
Structural type:
Purpose:
Treat duodenal ulcer, gastric ulcer and reflux esophagitis, gastric ulcer or recurrent duodenal ulcer caused by low-dose aspirin. Eradication of Helicobacter pylori, adjuvant treatment of the following diseases: gastric ulcer, duodenal ulcer, gastric MALT lymphoma, idiopathic thrombocytopenic purpura, early gastric cancer, Helicobacter pylori infectious gastritis.
Manufacturing
