Cefaclor

English name：	Cefaclor
Chemical name：	(6R,7R)-7-[(R)-2-Amino-2-phenylacetamido)-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate
Category involved：	bulk pharmaceutical chemicals
Structural type：
CAS#：	70356-03-5
Molecular formula：	C15H14ClN3O4S • H2O
Molecular weight：	385.82
Quality standard：	Comply with the standards of USP, EP, CP
Application：	Chemical synthesis antibiotics raw materials can be used for the treatment of infections caused by staphylococcus, streptococcus (except for enterococcus), pneumococcus, influenza bacteria, escherichia coli, Klebsiella and proteus mirabilis.
Storage condition：	Shading, sealed preservation.
Packaging specifications：	25 KG/barrel, cardboard drum, lined with a layer of polyethylene bag and an aluminum foil bag.

Properties

Cefaclor is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefaclor binds to and inactivates penicillin-binding proteins (PBP) located in bacterial cytoplasmic membranes. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

CAS No.

70356-03-5

Formula

C15H16ClN3O5S

Molecular Mass

385.82300

Exact Mass

385.05000

PSA

147.26000

Logp

1.58610