Dactinomycin

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Dactinomycin

CAS NO.： 50-76-0

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Specification： USP, CP

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Lead Time： 14-30 days

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Packing： 25KG/Fibre Drum

Product Detail

Properties

Dactinomycin

CAS No.: 50-76-0

Molecular formula: C62H86N12O16

Molecular weight: 12542.5

Melting point: 1251-253 ℃

Appearance: bright red crystalline powder

Application: antitumor drugs

Properties

Dactinomycin is an intravenously administered, antineoplastic antibiotic that is used in the treatment of solid tumors in children and choriocarcinoma in adult women. In high doses, dactinomycin can cause severe liver injury including sinusoidal obstruction syndrome. Dactinomycin is an Actinomycin. The mechanism of action of dactinomycin is as a Nucleic Acid Synthesis Inhibitor, and Protein Synthesis Inhibitor.

CAS No.

50-76-0

Formula

C62H86N12O16

Molecular Mass

1255.42000

Exact Mass

1254.63000

PSA

359.98000

Logp

2.37360

IUPAC

2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide

Matter Classification

organic

Category

Melting Point

251-253 °C

Density

1.42 g/cm3

Boiling Point

1386ºC

Flash Point

792.1ºC

Appearance

Bright red crystalline powder

Acidity and Basicity

neutral

HS Code

29419090

Export Formalities

UN No.

3462

DG-Class

6.1

Risk Code

R28-61-40-45-26/27/28

Safety Label

T+

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Dactinomycin