Mitomycin

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Mitomycin

CAS NO.： 50-07-7

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Lead Time： 14-30 days

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Packing： 25KG/Fibre Drum

Product Detail

Properties

Mitomycin

CAS No.: 50-07-7

Molecular formula: C15H18N4O5

Molecular weight: 334.32

Melting point: 360 ℃

Appearance: dark blue gray crystalline powder

Application: antitumor drugs

Properties

Mitomycin is a methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. Bioreduced mitomycin C generates oxygen radicals, alkylates DNA, and produces interstrand DNA cross-links, thereby inhibiting DNA synthesis. Preferentially toxic to hypoxic cells, mitomycin C also inhibits RNA and protein synthesis at high concentrations.

CAS No.

50-07-7

Formula

C15H18N4O5

Molecular Mass

334.32700

Exact Mass

334.12800

PSA

146.89000

Logp

0.01610

IUPAC

[(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

Matter Classification

organic

Category

Melting Point

360 °C

Density

1.56g/cm3

Boiling Point

581.8ºC

Flash Point

305.6ºC

Appearance

Dark blue gray crystalline powder

Acidity and Basicity

reducibility, alkalinity

HS Code

29419090

Export Formalities

UN No.

3462

DG-Class

6.1

Risk Code

R25-40-22-45-26/27/28

Safety Label

T，Xn,T+

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Mitomycin