Doxorubicin Hydrochloride

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CAS NO.： 25316-40-9

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Specification： USP, EP, CP, JP

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Lead Time： 14-30 days

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Packing： 25KG/Fibre Drum

Product Detail

Properties

Doxorubicin HCl

CAS No.: 25316-40-9

Molecular formula: C27H30ClNO11

Molecular weight: 579.98

Melting point: 216 ℃

Appearance: orange red crystalline solid

Application: antitumor drugs

Properties

Doxorubicin is also known as adriamycin hydrochloride. Pure doxorubicin is an orange lyophilized powder, soluble in water, melting point is 216 ℃. Doxorubicin (ADM), also known as adriamycin, is commonly used in clinical chemotherapy of human cancer. Doxorubicin is a kind of chemical semi synthetic anthracycline antibiotics. Like daunorubicin and other anthracyclines, doxorubicin can intercalate DNA and affect DNA synthesis. It is commonly used in the treatment of various cancers, such as hematological malignancies, solid tumors and soft tissue sarcomas. In clinical practice, human medicine is usually combined with other drugs to treat tumors.

CAS No.

25316-40-9

Formula

C27H30ClNO11

Molecular Mass

579.98000

Exact Mass

579.15100

PSA

206.07000

Logp

1.50360

IUPAC

(7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride

Matter Classification

organic

Category

Melting Point

216ºC

Boiling Point

810.3ºC

Flash Point

443.8ºC

Appearance

orange to dark red.solid

Acidity and Basicity

acidness, reducibility

HS Code

29419090

Export Formalities

Risk Code

R45-22-40-26/27/28-36/38

Safety Label

T,T+,Xi

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Doxorubicin HCl