Epirubicin Hydrochloride

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CAS NO.： 56390-09-1

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Lead Time： 14-30 days

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Packing： 25KG/Fibre Drum

Product Detail

Properties

Epirubicin HCl

CAS No.: 56390-09-1

Molecular formula: C27H30ClNO11

Molecular weight: 579.98

Melting point: 185℃

Appearance: orange red crystalline solid

Application: antitumor drugs

Properties

Epirubicin hydrochloride is the main isomer of doxorubicin, which is the trans configuration of C4 hydroxyl group in the amino sugar part of doxorubicin. It can directly embed into DNA, form a complex with the double helix structure of DNA, block the formation of DNA dependent RNA, and have the kinetic energy to form superoxide radicals. Single drug has a broad spectrum of inhibitory effects on many kinds of tumors, including breast cancer, malignant lymphoma, soft tissue sarcoma and gastric cancer. Studies have shown that the drug also has antitumor activity on malignant melanoma and colon cancer.

CAS No.

56390-09-1

Formula

C27H30ClNO11

Molecular Mass

579.98000

Exact Mass

579.15100

PSA

206.07000

Logp

1.50360

IUPAC

(7S,9S)-7-[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride

Matter Classification

organic

Category

Melting Point

185ºC

Density

1.61g/cm3

Boiling Point

810.3ºC

Flash Point

443.8ºC

Appearance

red to deep red powder

Acidity and Basicity

acidness, reducibility

HS Code

29419090

Export Formalities

Risk Code

R22-63-62-46-40

Safety Label

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Epirubicin HCl