Irbesartan

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Irbesartan

CAS NO.： 138402-11-6

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Specification： 99%

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Lead Time： 14-30 days

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

Irbesartan

Chinese Name: 厄贝沙坦

CAS No.: 138402-11-6

Molecular formula: C₂₅H₂₈N₆O

Structural type:

Melting point: 180-181 °C

Application: antihypertensive drugs

Properties

Irbesartan is an angiotensin II receptor inhibitor, which can be divided into AT1 and AT2. Irbesartan can inhibit the transformation of Ang Ⅰ into ang Ⅱ by selectively blocking the AT1 receptor of ANGLI, and specifically antagonize the angiotensin converting enzyme 1 receptor. The antagonism of irbesartan to AT1 is 8500 times that of AT2, It can inhibit the vasoconstriction and the release of aldosterone. This product does not inhibit angiotensin converting enzyme, renin, other hormone receptors, and ion channels related to blood pressure regulation and sodium balance. Irbesartan is the most effective drug in the treatment of hypertension and cardiovascular disease.

CAS No.

138402-11-6

Formula

C25H28N6O

Molecular Mass

428.52900

Exact Mass

428.23200

PSA

87.13000

Logp

4.15090

IUPAC

2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one

Matter Classification

organic

Category

Melting Point

180-181°C

Density

1.3 g/cm3

Boiling Point

648.6ºC

Flash Point

346ºC

Appearance

White crystalline powder

Acidity and Basicity

acidness, alkalinity

HS Code

29339900

UN No.

3276

DG-Class

6.1

Risk Code

R22

Safety Label

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Irbesartan