Milbemite

CAS:129496-10-2

Molecular formula：C₁₂₆H₁₇₆N₄O₂₈

Molecular weight：2194.76

Appearance:White like solid

Purpose：The utility model relates to a new antiparasitic drug for pets, which is a special drug for the prevention and treatment of internal and external parasites in dogs and cats. It can effectively prevent heartworm, hookworm, roundworm, whipworm, Ascaris and other internal parasites, as well as external parasites such as hair follicle worm, scabies, lice and fleas

Structural formula:

Properties

Milbeoxime is a macrolide antibody endoparasite and an oxime derivative of milbemycin A3 and A4. Milbeoxime can bind glutamate gated chloride channels and act on intestinal nematodes, lung and heart worms. Milbeoxime has a broad spectrum of antiparasitic effects, and has good repellent and killing effects on internal and external parasites, especially nematodes and arthropods.

CAS No.

129496-10-2

Formula

C126H176N4O28

Molecular Mass

2194.76000

Exact Mass

2193.25000

PSA

427.24000

Logp

20.79420

IUPAC

(1R,4S,5'S,6R,6'R,8R,10E,13R,14E,16E,20R,21E,24S)-6'-ethyl-24-hydroxy-21-hydroxyimino-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one;(1R,4S,5'S,6R,6'R,8R,10E,13R,14E,16E,20R,21Z,24S)-6'-ethyl-24-hydroxy-21-hydroxyimino-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one;(1R,4S,5'S,6R,6'R,8R,10E,13R,14E,16E,20R,21E,24S)-24-hydroxy-21-hydroxyimino-5',6',11,13,22-pentamethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one;(1R,4S,5'S,6R,6'R,8R,10E,13R,14E,16E,20R,21Z,24S)-24-hydroxy-21-hydroxyimino-5',6',11,13,22-pentamethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one

Matter Classification

organic

Category

Melting Point

169.6-177.4°

Flash Point

412 ℃

Appearance

white solid

Acidity and Basicity

acidness

HS Code