Properties: It is light yellow crystalline powder at room temperature, odorless and tasteless. It is dissolved in ethanol and almost insoluble in water,
Application: to produce good curative effect on positive or negative symptoms of schizophrenia.
Quality standard: BP, CP, USP, EP
Properties
Summary
Clozapine was the first atypical antipsychotic approved for treatment of schizophrenia. Because it is associated with severe and potentially fatal side effects (agranulocytosis), its use is restricted to refractory schizophrenia, and monitoring during therapy is required. Clozapine therapy is associated with serum aminotransferase elevations and in rare instances has been linked to clinically apparent acute liver injury.
Manufacturing
