The trade name of paliperidone is investa. It is an amorphous antipsychotic drug developed by Johnson & Johnson Janssen Pharmaceutical Company. Rita is a long-term version of paliperidone using a osmotic controlled-release oral drug delivery system (OROS), which allows patients to take it once a day. Chemically, paliperidone is the main active substance produced by the metabolism of early amorphous antipsychotic risperidone. This medicine is used to treat schizophrenia, schizophrenic affective disorder. The off label use of this drug includes Tourette's disease, which can be significantly improved by using a low dose.