CAS:68-22-4
Molecular formula:C20H26O2
Molecular weight:298.41900
Appearance:white crystal
Synopsis:Norethisterone, a derivative of 19 demethyltestosterone, is an oral progesterone. Its progesterone activity is 4 times higher than that of progesterone, and its estrogen and androgen activities are weak. It can inhibit the secretion of hypothalamic luteinizing releasing hormone (LHRH). By stimulating the anterior pituitary, it can reduce the sensitivity of the body to LHRH, so as to block the release of gonadotropin and inhibit ovulation. After oral administration of this product for 0.5 ~ 4 hours, the blood concentration can reach the peak, and the half-life is 5 ~ 14 hours. Most of the metabolites are discharged from the body through the kidney.
Structural formula: