Artemether

Product introduction:

Artemether and benflumetol are two new antimalarial drugs with different structures and functions developed in recent years. Both drugs are usually treated with a single drug. Artemether is characterized by rapid killing of malaria parasites, but the killing is not complete, and the resurgence rate of residual parasites in patients' blood after treatment is high. White crystal or crystalline powder, bitter and odorless. This product is very soluble in acetone and chloroform, easily soluble in ethanol or ethyl acetate, and almost insoluble in water.

CAS：71963-77-4

Molecular formula: C₁₆H₂₆O₅

Molecular weight: 298.37

Structural type:

Product purpose:

Artemether has a direct killing effect on the erythrocytic stage of malaria parasite, has no effect on the tissue stage, has low toxicity to experimental animals, absorbs blocks in the body, distributes widely and excretes quickly. Electron microscope observation shows that the main action site of this product on mouse Plasmodium is the membrane structure, and its anti malaria mechanism is considered to interfere with the function of Plasmodium surface membrane mitochondria.