Pranoprofen (7), chemical name is α- Methyl-5h - [1] benzopyrano[ α， 3-b] pyridine-7-acetic acid is a non steroidal anti-inflammatory and analgesic drug developed by welfide company (formerly Jifu Pharmaceutical Co., Ltd., now Mitsubishi pharmaceutical); Qianshou Pharmaceutical Co., Ltd. developed it as an eye drops, which was listed in Japan under the trade name nifran in 1981; Among them, tablets and capsules are used for anti-inflammatory and analgesia of many diseases, such as chronic rheumatoid arthritis, osteoarthritis, low back pain, periarthritis of shoulder, neck shoulder wrist syndrome, periodontitis, gout, etc. they are also used for analgesia and anti-inflammatory after surgery, trauma and tooth extraction, as well as antipyretic and analgesia of acute upper respiratory tract infection; Eye drops can be used for the symptomatic treatment of external eyes and anterior eyes (blepharitis, conjunctivitis, keratitis, scleritis, superficial scleritis, iridocyclitis and postoperative inflammation), as well as the treatment of cataract, laser iridectomy, excimer laser subepithelial keratomileusis and dry eye.
IUPAC
2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid
Manufacturing
