Darunavir

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Darunavir

CAS NO.： 206361-99-1

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Specification： 99%

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Lead Time： 14-30 days

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

Darunavir

Chinese Name: 达芦那韦

CAS No.: 206361-99-1

Molecular formula: C27H37N3O7S

Molecular weight: 547.66

EINECS No.: 606-590-1

Melting point: 74-76 ℃

Density: 1.34g/cm3

Purpose: a new non peptide antiretroviral protease inhibitor for AIDS treatment.

Properties

Darunavir is an antiretroviral protease inhibitor that is used in the therapy and prevention of human immunodeficiency virus (HIV) infection and the acquired immunodeficiency syndrome (AIDS). Darunavir can cause transient and usually asymptomatic elevations in serum aminotransferase levels and has been linked to rare instances of clinically apparent, acute liver injury. In HBV or HCV coinfected patients, highly active antiretroviral therapy with darunavir may result of an exacerbation of the underlying chronic hepatitis B or C.

CAS No.

206361-99-1

Formula

C27H37N3O7S

Molecular Mass

547.66400

Exact Mass

547.23500

PSA

148.80000

Logp

4.42820

IUPAC

[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate

Matter Classification

organic

Category

Melting Point

74-76ºC

Density

1.34g/cm3

Appearance

White amorphous solid

Acidity and Basicity

reducibility

HS Code