Tetracycline

Introduction:

Tetracycline is an antibiotic synthesized by chlortetracycline catalyzed Dehalogenation biosynthesis. It is a broad-spectrum bacteriostatic agent with low toxicity. It has bactericidal effect at high concentration. In addition to the common gram-positive bacteria, Gram-negative bacteria and anaerobic bacteria, most Rickettsia, mycoplasma, chlamydia, atypical mycobacteria and spirochetes are also sensitive to this product. The effect of this product on Gram-positive bacteria is better than Gram-negative bacteria, but Enterococcus is resistant to it. Taking tetracycline family drugs during tooth development and mineralization, such as tetracycline, oxytetracycline, aureomycin, methylaureomycin and doxycycline, can be combined into tooth tissue to make the teeth colored, yellowish brown or dark gray.

Mechanism of action:

Inhibition of bacterial protein synthesis is the antibacterial mechanism of tetracyclines. By binding to 30S subunit, aminoacyl tRNA is prevented from binding to mRNA ribosome complex, and the formation of peptide chain is blocked and bacteriostatic.

Tetracycline for animals:

Tetracycline antibiotics for animals are a kind of broad-spectrum antibiotics with tetrabenzene structure. They are mainly divided into natural and semi synthetic antibiotics. They can be taken orally, have a wide antibacterial spectrum, have low toxicity, few allergies and serious drug resistance, but have weak inhibitory effect on bacterial growth (less than penicillins or streptomycin). Tetracycline antibiotics for animals mainly include oxytetracycline, tetracycline, aureomycin, doxycycline, minocycline, methylenemycin, etc. they have their own emphasis on the treatment effect, and the dosage requirements are also different. In the use of different types of livestock, we should pay attention to follow the doctor's advice or the requirements of the product manual.

CAS：60-54-8

Molecular formula: C22H24N2O8

Molecular weight: 444.43

Structural type: