IDRA21

Home

0086-571-8627 3270

service@chemball.com

Tert-Amyl Alcohol Acrylamide Sulphanilic Acid Isopropyl Acetate Potassium Sorbate

Home > API & Intermediate > Pharmaceutical Intermediates > IDRA21 Manufacturers > IDRA21

IDRA21

CAS NO.： 22503-72-6

FOB Price： NEGOTIABLE Get Latest Price

Specification： 99%

Documentation：

Lead Time： In Stock

Max Capacity： 0.5MT/Year

Packing： Customed Package

Overview

Properties

OVERVIEW

Product name: IDRA-21

Chemical name: 7-Chloro-3-Methyl-3,4-Dihydro-2H-1,2,4-Benzothiadiazine 1,1-Dioxide

CAS: 22503-72-6

Molecular formula: C8H9ClN2O2S

Molecular weight: 232.69

Content: 99%

Appearance: white powder

Properties

IDRA-21 is an ampakine drug and a benzothiadiazine derivative. IDRA-21 is a chiral molecule, with (+)-IDRA-21 being the active form. IDRA-21 shows nootropic effects in animal studies, significantly improving learning and memory. It is around 10–30 times more potent than aniracetam in reversing cognitive deficits induced by alprazolam or scopolamine, and produces sustained effects lasting for up to 48 hours after a single dose. The mechanism for this action is thought to be through promoting the induction of long-term potentiation between synapses in the brain. IDRA-21 does not produce neurotoxicity under normal conditions, although it may worsen neuronal damage following global ischemia after stroke or seizures. In comparison to the benzoylpiperidine derived ampakine drugs, IDRA-21 was more potent than CX-516, but less potent than CX-546. Newer benzothiadiazide derivatives with greatly increased potency compared to IDRA-21 have been developed, but these have not been researched to the same extent, with the benzoylpiperidine and benzoylpyrrolidine CX-series of drugs being favoured for clinical development, most likely due to more favourable toxicity profiles at high doses.

CAS No.

22503-72-6

Formula

C8H9ClN2O2S

Molecular Mass

232.68700

Exact Mass

232.00700

PSA

66.58000

Logp

2.93740

IUPAC

7-chloro-3-methyl-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine 1,1-dioxide

Matter Classification

organic

Category

Melting Point

209 °C(Solv: acetic acid (64-19-7))

Density

1.394g/cm3

Boiling Point

405.1ºC at 760mmHg

Flash Point

198.8ºC

Appearance

Off-White to Pale Yellow Powder

HS Code

29420000

Send your message to this supplier

To：

Suzhou Myland Pharm & Nutrition Inc.

Not exactly what you want? One request, multiple quotations Get Quotations Now >>

Supplier's main products

CAS: 1208313-97-6

Trans-3,5-dimethoxystilbene-4′-O-β-D-glucopyranoside

CAS: 38967-99-6

Spermidine Trihydrochloride

Spermine Tetrahydrochloride

CAS: 10338-51-9

Aminolevulinic acid Phosphate

CAS: 868074-65-1

7,8-Dihydroxyflavone

CAS: 38183-03-8

Calcium Ketoglutarate Monohydrate

CAS: 71686-01-6

25KG/Fibre Drum

CAS: 154992-24-2

9-Methyl-9h-Pyrido[3,4-b]Indole

2-[[2-[5-Methyl-3-(Trifluoromethyl)Pyrazol-1-yl]Acetyl]Amino]-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide

CAS: 489408-02-8

N-acetylcysteine Ethyl Ester

CAS: 59587-09-6

2-[(2-Methoxyphenyl)[(4-Methylphenyl)Sulfonyl]Amino]-N-(4-Methoxy-3-Pyridinyl)Acetamide

CAS: 1890208-58-8

1-(1-Adamantylcarbonyl) Proline ACA

CAS: 35084-48-1

N-Oleoylethanolamine

CAS: 21414-41-5

TLB 150 Benzoate

CAS: 1208070-53-4

CAS: 159752-10-0

1-(Methylsulfonyl)Spiro[Indoline-3,4'-Piperidine]

CAS: 178261-41-1

Adenosine Triphosphate Disodium

25KG/Fibre Drum

N-Methyl-Dl-Aspartic Acid

CAS: 17833-53-3

25KG/Fibre Drum

Spirostan-6-One, 3,5-Dihydroxy-, (3β,5α,25R)-

CAS: 56786-63-1

CAS: 1146963-51-0

CAS: 112193-35-8

(S)-Ethyl 2-(1-(2-Phenylacetyl)Pyrrolidine-2-Carboxamido)Acetate

CAS: 157115-85-0

KG/Customed Package

Galanthamine Hydrobromide

KG/Customed Package

CAS: 22503-72-6

KG/Customed Package

Choline Glycerophosphate

CAS: 28319-77-9

KG/Customed Package

CAS: 314728-85-3

KG/Customed Package

CAS: 110958-19-5

KG/Customed Package

CAS: 68497-62-1

KG/Customed Package

CAS: 72432-10-1

KG/Customed Package

CAS: 77191-36-7

KG/Customed Package

Fonturacetam Hydrazide

CAS: 77472-71-0

KG/Customed Package

KG/Customed Package

Citicoline Sodium

CAS: 33818-15-4

KG/Customed Package

Methyl 3-(2-(Benzyl(Methyl)Amino)Ethyl)Benzoate Hydrochloride

CAS: 51352-87-5

KG/Customed Package

CAS: 27113-22-0

KG/Customed Package

Palmitoyl Ethanolamide

KG/Customed Package

Magnesium Taurate

CAS: 334824-43-0

KG/Customed Package

Nicotinamide Ribose

CAS: 23111-00-4

KG/Customed Package

β-Nicotinamide Mononucleotide

KG/Customed Package

β-Nicotinamide Adenine Dinucleotide

KG/Customed Package

Beta-Nicotinamide Adenine Dinucleotide, Disodium salt

KG/Customed Package

L-Threonic Acid Calcium Salt

CAS: 70753-61-6

KG/Customed Package

L-Threonic Acid Magnesium Salt

CAS: 778571-57-6

KG/Customed Package

Tianeptine Sodium Salt Hydrate###Tianeptine Sodium Salt

CAS: 30123-17-2

KG/Customed Package

Tianeptine Semisulfate Monohydrate

CAS: 1224690-84-9

KG/Customed Package

Tianeptine Acid

CAS: 66981-73-5

KG/Customed Package

CAS: 910463-68-2

KG/Customed Package

Company Logo

Suzhou Myland Pharm & Nutrition Inc.

11YRS

Business Type：

Manufacturing

Country/Region：

Jiangsu, China

Contacts：

Eason Shi

Position Title：

Sales Manager

Tel：

0086-512-66706057-8011

Email：

szmyland@chemmail.net

Get Free Samples

Less than 1KG required

WhatsApp

Connect Us on WhatsApp

0086-13958034490

open WhatsApp

Send Email

Whatsapp

TOP