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Tert-Amyl Alcohol Acrylamide Sulphanilic Acid Isopropyl Acetate Potassium Sorbate

Home > API & Intermediate > Blood System Drugs > Pradaxa Manufacturers > Dabigatran Etexilate

Pradaxa

CAS NO.： 211915-06-9

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Specification： ≥99%

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Lead Time： 14-30 days

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Packing： 25KG/Fibre Drum

Product Detail

Properties

Dabigatran Etexilate

Category	API
Product Name	Dabigatran etexilate
Structure
CAS No.	211915-06-9

Properties

Dabigatran ester is a new synthetic direct thrombin inhibitor. It is the precursor of dabigatran and belongs to non peptide thrombin inhibitor. After oral absorption through gastrointestinal tract, it is transformed into dabigatran with direct anticoagulant activity in vivo. Dabigatran binds to the fibrin specific binding site of thrombin and prevents the cleavage of fibrinogen into fibrin, thus blocking the final step of coagulation waterfall network and thrombosis. Dabigatran can dissociate from fibrin thrombin conjugate and play a reversible anticoagulant effect

CAS No.

211915-06-9

Formula

C34H41N7O5

Molecular Mass

627.73300

Exact Mass

627.31700

PSA

154.03000

Logp

6.37590

IUPAC

ethyl 3-[[2-[[4-[(E)-N'-hexoxycarbonylcarbamimidoyl]anilino]methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate

Matter Classification

organic

Category

Melting Point

128-129°

Density

1.24 g/cm3

Boiling Point

827.9ºC at 760 mmHg

Flash Point

454.5ºC

Appearance

white powder

HS Code

2933990099

UN No.

0.0

DG-Class

0.0

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Zhejiang Liaoyuan Pharmaceutical Co.,Ltd.

30YRS

Business Type：

Manufacturing

Country/Region：

Zhejiang, China

Contacts：

Manager Ying

Position Title：

Sales Director

Tel：

0086-576-85300959

Email：

liaoyuan@chemmail.net

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