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CAS:120511-73-1
Molecular Formula:C17H19N5
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Ici-D-1033; Zd-1033; Anastrol; 1,3-Benzenediacetonitrile; Anastrazole; 2,2'-(5-((1H-1,2,4-Triazol-1-Yl)Methyl)-1,3-Phenylene)Bis(2-Methylpropanenitrile); 4-Triazol-1-Ylmethyl)-1; Anastrolozole; Anatrozole; Anastrozol; Arimidex; 1-[3,5-Di-(1-Methyl-1-Cyano)-Ethyl]-Benzyl-1,2,4-Triazole; α,α,α’,α'-Tetramethyl-5-(1H-1,2,4-Triazol-1-Ylmethyl)-1,3-Benzenediacetonitrile; 2-[3-(2-Cyanopropan-2-Yl)-5-(1,2,4-Triazol-1-Ylmethyl)Phenyl]-2-Methylpropanenitrile; α1,α1,α3,α3-Tetramethyl-5-(1H-1,2,4-Triazol-1-Ylmethyl)-1,3-Benzenediacetonitrile
Brief Introduction
Anastrozole is a potent selective three azole aromatase inhibitor, which inhibits the cytochrome P-450 dependent aromatase and thus blocks the biosynthesis of estrogen. Estrogen is a major factor in stimulating the growth of breast cancer cells. Letrozole is suitable for postmenopausal women with advanced breast cancer, and is used for second-line treatment after the failure of anti estrogen therapy.
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CP/USP
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Pharm Grade
25kg
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Fibre Drum
CAS:122-11-2
Molecular Formula:C12H14N4O4S
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4-Amino-N-(2,6-Dimethoxy-4-Pyrimidinyl)Benzenesulfonamide; 4-Amino-N-(2,6-Dimethoxypyrimidin-4-Yl)Benzenesulfonamide; Benzenesulfonamide, 4-Amino-N-(2,6-Dimethoxy-4-Pyrimidinyl)-; Sulphadimethoxine; Sulfadimethoxin; Sulfadimethoxydiazine
Brief Introduction
Sulfonamides that block dihydrofolate synthesis by inhibiting dihydrofolate synthase. Mode of action: inhibit folate synthesis in prokaryotes. Antibacterial spectrum: resistance mechanism of Gram-positive bacteria, Gram-negative bacteria and Chlamydia: change of dihydrofolate synthase or alternative path of folate synthesis.
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CAS:122111-03-9
Molecular Formula:C9H12ClF2N3O4
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2'-Deoxy-2',2'-Difluorocytidine; Gemcitabine Hcl(Tabines); 2’,2’-Difluorodeoxycytidinemonohydrochloride; 2’-Deoxy-2’,2’-Difluorocytidinemonohydrochloride; 2’-Deoxy-2’,2’-Difluoro-Cytidinmonohydrochloride; Gemzar; Ly188011; Ly188011 Hydrochloride; 2',2'-Difluoro-2'-Deoxycytidine
Brief Introduction
Gemcitabine hydrochloride is a synthetic new type of two fluoronucleoside antitumor drug developed by Eli Lilly. It was approved in 1995 in South Africa, Sweden, Holland, Australia and other countries. In 1996, the US Food and Drug Administration approved the first line treatment for non-small cell lung cancer and pancreatic cancer. Gemcitabine hydrochloride, a nucleoside homologue, is a cell cycle specific antitumor drug. It mainly kills cells in S phase (DNA synthesis) and blocks the transition of cell proliferation from G1 to S phase. Gemcitabine is suitable for the treatment of advanced or metastatic pancreatic cancer and locally advanced or metastatic non-small cell lung cancer, advanced and non-small cell lung cancer, pancreatic cancer, bladder cancer, breast cancer and other solid tumors.
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CAS:1229194-11-9
Molecular Formula:C31H40ClN7O8S2
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Edoxaban; Lixiana; Savaysa; Edoxaban Tosylate Hydrate
Brief Introduction
Edoxaban is an oral tablet of selective coagulation factor Xa inhibitor for the prevention and treatment of deep venous thrombosis and pulmonary embolism. It is used to reduce the risk of stroke and systemic embolism in patients with non valvular atrial fibrillation (NVAF). At present, it has three specifications: 60mg, 30mg and 15mg.
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CAS:125971-94-0
Molecular Formula:C14H23NO4
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ATS-8; Tert-Butyl (4R,6R)-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate; (4R-Cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate; (4R,6R)-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid Tert-Butyl Ester; Tert-Butyl 6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxolane-4-Acetate; (4R,6R)-T-Butyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate; (4R,Cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate; (4R,3R)-Tert-Butyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate; (4R-Cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate (Ats-8); Tert-Butyl[(4R,6R)-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxan-4-Yl]Acetate; Atorvastatin Calcium Intermediate ats-8; ATS-8: (4R-cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate; (4R,CIS)-1,1-Dimethylethyl-6- Cyanomethyl-2,2-Dimethyl-1,3- Dioxane-4-Acetate (ATS-8)
Brief Introduction
Tert-butyl 2-[(4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate is used as an intermediate of atorvastatin. Atorvastatin is a selective competitive HMG CoA reductase inhibitor, which can significantly reduce LDL CH and triglyceride, but does not cause the redistribution of triglyceride, but constantly reduces TG in all lipoprotein components. It is suitable for the patients with primary hypercholesterolemia, heterozygous familial hypercholesterolemia or mixed hyperlipidemia, whose diet control can not effectively reduce the average total cholesterol, low density lipoprotein cholesterol and triglyceride. It is also suitable for patients with heterozygous familial hypercholesterolemia who have diet control at the same time.
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