API & Intermediate

Ulinastat acetate is a new oral emergency contraceptive, and the efficacy of emergency contraception will not decline with the delay of medication time. At the same time, it has good safety and tolerance.

Pyruvate is a component of human body, which is mainly involved in the metabolism of sugar and fat in human body, and is also one of the intermediate products of carbohydrate metabolism. Pyruvic acid and its salt are widely used in medicine field, and are used to produce tranquilizers, antioxidants, disease resistant agents, synthetic drugs for hypertension and so on. Pyruvic acid can be used in the synthesis of medicine and amino acids, which can improve the production efficiency, especially in pharmaceutical industry, it can shorten the process and simplify the process. For example, 2-phenyloctenic acid, which is made of this product, is a kind of antipyretic and analgesic and diuretic drug. Using this product as raw material can greatly reduce the production cost. It is also used as the anti tuberculosis drug, calcium isoniazide pyruvate, hormone synthesis, pyreniumapamote as an insecticide, and also as pesticide raw materials. The tryptophan can be produced by biochemical reaction from pyruvic acid, indole and ammonia, and it can also be used to produce MSG and spices.

Tetrachloroethylene is a colorless, volatile, nonflammable, liquid, chlorinated hydrocarbon with an ether-like odor that may emit toxic fumes of phosgene when exposed to sunlight or flames. Tetrachloroethylene is mainly used as a cleaning solvent in dry cleaning and textile processing and in the manufacture of fluorocarbons. Exposure to this substance irritates the upper respiratory tract and eyes and causes neurological effects as well as kidney and liver damage. Tetrachloroethylene is reasonably anticipated to be a human carcinogen and may be linked to an increased risk of developing skin, colon, lung, esophageal, and urogenital tract cancer as well as lymphosarcoma and leukemia.

Ursodeoxycholic acid is a chemical preparation of natural bile acid isolated from bear bile juice. It is a stereoisomer of chenodeoxycholic acid. Its litholytic effect and curative effect are similar to chenodeoxycholic acid, but the course of treatment is short and the dosage is small. It is a kind of hydrophilic cholic acid and a kind of cholesterol stone dissolving agent. It can reduce the secretion of cholesterol by liver, reduce the saturation of cholesterol in bile, promote the secretion of bile acid, increase the solubility of cholesterol in bile, dissolve cholesterol stones or prevent the formation of stones. It can increase the amount of bile secretion, relax the sphincter of bile duct mouth, produce cholagogic effect, which is conducive to the discharge of stones. This product can not dissolve other types of gallstones. Ursodeoxycholic acid is suitable for the treatment of cholesterol gallstones, hyperlipidemia, bile secretion disorders, primary biliary cirrhosis, chronic hepatitis, bile reflux gastritis and prevention of acute rejection and reaction of liver transplantation. The stone dissolving effect of this product is slightly weaker than that of chenodeoxycholic acid.

Milbeoxime is a macrolide antibody endoparasite and an oxime derivative of milbemycin A3 and A4. Milbeoxime can bind glutamate gated chloride channels and act on intestinal nematodes, lung and heart worms. Milbeoxime has a broad spectrum of antiparasitic effects, and has good repellent and killing effects on internal and external parasites, especially nematodes and arthropods.