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Inhibitors

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CAS:571190-30-2
Molecular Formula:C24H29N7O2
Ibrance(Trade name); Pabcilib; Pabosi Ni
Brief Introduction
Pabcicilib is an inhibitor of cyclin dependent kinase (CDK) 4 and 6. Cyclin D1 and CDK4 / 6 are downstream signaling pathways leading to cell proliferation. In vitro, the proliferation of ER positive breast cancer cells was inhibited by blocking the progression from G1 to S phase. Compared with the treatment of each drug alone, the combination of pabacib and anti estrogen resulted in decreased phosphorylation of retinoblastoma protein (RB), decreased E2F expression and signal, and prevented growth. In vitro treatment of ER positive breast cancer cell lines with combination of pabacib and anti estrogen resulted in increased cell senescence, which lasted up to 6 days after drug removal.
CAS:917389-32-3
Molecular Formula:C29H28F4N4O4
AIC246; CS-2799; MK-8828; UNII-1H09Y5WO1F; (4S)-8-Fluoro-3,4-Dihydro-2-[4-(3-Methoxyphenyl)-1-Piperazinyl]-3-[2-Methoxy-5-(Trifluoromethyl)Phenyl]-4-Quinazolineacetic acid; -Quinazolineacetic acid, 8-Fluoro-3,4-Dihydro-2-[4-(3-Methoxyphenyl)-1-Piperazinyl]-3-[2-Methoxy-5-(Trifluoromethyl)Phenyl]-, (4S)-
Brief Introduction
Letimovir is a novel anti CMV compound, which targets the virus terminal enzyme complex. Viruses resistant to DNA polymerase inhibitors also have activity.
CAS:737789-87-6
Molecular Formula:C29H29F2N7O5S
1-(4-(1-(2,6-Difluorobenzyl)-5-((Dimethylamino)Methyl)-3-(6-Methoxypyridazin-3-yl)-2,4-Dioxo-1,2,3,4-Tetrahydrothieno[2,3-d]Pyrimidin-6-yl)Phenyl)-3-Methoxyurea; TAK-385
Brief Introduction
Relugolix is an oral gonadotropin releasing hormone receptor antagonist
CAS:6055-19-2
Molecular Formula:C7H17Cl2N2O3P
Cyclophosphamide Hydrate; Cyclophosphamide Monohydrate; 2-[Bis(2-Chloroethyl)Amino]Tetrahydro-2H-1,3,2-Oxazaphosphorine 2-Oxide Hydrate; N,N-bis(2-Chloroethyl)-2-oxo-1,3,2Lambda5-Oxazaphosphinan-2-Amine;Hydrate
Brief Introduction
Cyclophosphamide is a nitrogen mustard alkylating agent that connects alkyl groups to guanine bases of DNA. Cross linked with DNA, resulting in DNA strand breakage and mutation. It has cytotoxic effect.
CNY 90.3 Million
53280m²
100-500 People
Manufacturing Manufacturing
Product Photo Specification Grade Max Capacity Certificates Package
≥99.0% Pharm Grade - -
20kg / Fibre Drum
Main products:
Cyclophosphamide /Benzhexol Hydrochloride /Folic Acid /Protamine Sulfate /Ilepcimide /Promestriene /5-Fluorouracil /Methotrexate /Chlorquinaldol /Cytarabine Hydrochloride /Ancitabine Hydrochloride /Tamoxifen Citrate /Acetazolamide /Ifosfamide /Glycine /Levodopa /Nifedipine /Zinc Gluconate /Nimustine Hydrochloride /Hydrocortisone Butyrate /Sulfamethoxazole
CAS:74103-07-4
Molecular Formula:C19H24N2O6
2-Amino-2-(Hydroxymethyl)Propane-1,3-Diol,5-Benzoyl-2,3-Dihydro-1H-Pyrrolizine-1-Carboxylic Acid; Rac Ketorolac Tromethamine Salt; Ketorolac Tris Salt; Toradol; Acular
Brief Introduction
Ketorolac tromethamine is an alcohol organic compound. Its biological activity is related to L-S (-) and can inhibit prostaglandin biosynthesis.
Hainan Zhuoke Pharmaceutical Co., Ltd.
CNY 100 Million
19980m²
Less Than 50 People
CRO CRO
Product Photo Specification Grade Max Capacity Certificates Package
YBH03222006,CP Pharm Grade - -
10kg / Fibre Drum
Main products:
Ketorolac Tromethamine /Sulpiride /Diatrizoic Acid Dihydrate /Meglumine /Mycophenolate Mofetil /Aztreonam /Cefamandole Nafate /Creatine Phosphate Disodium Salt
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