Tacrolimus monohydrate (FK506 monohydrate) is a macrolide compound that binds to the FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase, thereby inhibiting T lymphocyte signal transduction and IL-2 transcription. Has strong immunosuppressive properties.

Suppliers

Fishfa Biogenics

USD 5 Million

50-100 People

Manufacturing Manufacturing

Specification	Grade	Max Capacity	Certificates	Package

97% to 102%	Pharm Grade	180 tons/year	COA	1kg / Fibre Drum
98.0 % to 102.0%	Pharm Grade	180 tons/year	COA	1kg / Fibre Drum

Main products:

Tacrolimus Monohydrate

Lafutidine

CAS:118288-08-7

Molecular Formula:C22H29N3O4S

Alias

More Information

(Z)-Inyl)Oxy)-2-Butenyl); Lafutidine(Subjecttopatentfree); Protecadin; Enyl)Acetamide; Rac-2-(Furfurylsulfinyl)-N-[(Z)-4-{[4-(Piperidinomethyl)-2-Pyridyl]Oxy}But-2-Enyl]Acetamide; (+/-)-2-(Furfurylsulfinyl)-N-[4-[4-(Piperidinomethyl)-2-Pyridyl]Oxy-(Z)-2-Butenyl]Acetamide; N-(4-(4-Piperidinylmethyl)Pyridyl-2-Oxy)Butenyl-2-(Furfurylsulfinyl)Acetamide; 2-((Furan-2-Ylmethyl)Sulfinyl)-N-(4-((4-(Piperidin-1-Ylmethyl)Pyridin-2-Yl)Oxy)But-2-En-1-Yl)Acetamide; (Z)-2-((Furan-2-Ylmethyl)Sulfinyl)-N-(4-((3-(Piperidin-1-Ylmethyl)Pyridin-2-Yl)Oxy)But-2-En-1-Yl)Acetamide; Adefovir Dipivioxil; (Z)-2-((Furan-2-Ylmethyl)Sulfinyl)-N-(4-((3-(Piperidin-1-Ylmethyl)Pyridin-2-Yl)Oxy)But-2-En-1-Yl);

Brief Introduction

Lafutidine, is a special histamine H2 receptor antagonist with acid inhibition and gastrointestinal mucosal protection. The drug inhibits gastric acid secretion by antagonizing histamine H2 receptor. The blocking ability of histamine H2 receptor is 2-85 times that of traditional histamine H2 receptor antagonists. The acid inhibition effect is strong and lasting, and can continuously inhibit the basic secretion of gastric acid, pepsin, nocturnal secretion, tetrapeptide gastrin, uracholine Gastric acid secretion caused by stimulating factors such as gastric dilation.

Suppliers

Shandong Qidu Pharmaceutical Co.,Ltd.

CNY 90 Million

399600m²

1000+ People

Manufacturer Manufacturing

Product Photo	Specification	Grade	Max Capacity	Certificates	Package

	CP	Pharm Grade	-	-	0.5kg / BOTTLE

Main products:

Lafutidine /Hydroxyethyl Starch /Metadoxine /Tropisetron Hydrochloride /α-Lipoic Acid /L-Carnitine

Midostaurin

CAS:120685-11-2

Molecular Formula:C35H30N4O4

Alias

More Information

4'-N-Benzoylstaurosporine; Pkc 412,[9S-(9α,10β,11β,13α)]-N-(2,3,10,11,12,13-Hexahydro-10-Methoxy-9-Methyl-1-Oxo-9,13-Epoxy-1H,9H-Diindolo[1,2,3-Gh:3',2',1'-Lm]Pyrrolo[3,4-J][1,7]Benzodiazonin-11-Yl)-N-Methylbenzamide; Cgp 41 251; 4'-N-Benzoyl Staurosprine; Benzoylstaurosporine

Brief Introduction

Midostaurin (PKC412) is a multi-target protein kinase inhibitor being investigated for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). It is a semi-synthetic derivative of staurosporine, an alkaloid from the bacterium Streptomyces staurosporeus, and is active in patients with mutations of CD135 (FMS-like tyrosine kinase 3 receptor, FLT3). After successful Phase II clinical trials, a Phase III trial for AML has started in 2008. It is testing midostaurin in combination with daunorubicin and cytarabine. In another trial, the substance has proven ineffective in metastatic melanoma.

Suppliers

Hubei Honch Pharmaceutical Co.,Ltd.

CNY 34.6 Million

19980m²

100-500 People

Manufacturing Manufacturing

Product Photo	Specification	Grade	Max Capacity	Certificates	Package

	INH	Pharm Grade	-	-	25kg / Fibre Drum

Main products:

Midostaurin /Vinorelbine L-Tartrate /Vincristine Sulfate /Vincaleukoblastine Sulfate /Mitomycin C /Bortezomib /Epothilone B /Ixabepilone /Staurosporine /Melphalan Hydrochloride /Lufenuron /Nitenpyram /Doramectin /Milbemite

Lubiprostone

CAS:136790-76-6

Molecular Formula:C20H32F2O5

Alias

More Information

13,14-Dihydro-15-Keto-Pgd2; 13,14-Dihydro-15-Ketoprostadlandin D2; 13,14-Dihydro-15-Keto-16,16-Difluoro-Prostaglandin E1; 9Alpha-Hydroxy-11,15-Dioxo-Prost-5Z-En-1-Oic Acid; 13,14-Dihydro-15-Keto Prostaglandin D2 Lipid Maps Ms Standard; Dk-Pgd2; 13,14-Dihydro-15-Keto Pd2; 13,14-Dihydro-15-Keto-Prostaglandin D2; 13,14-Dihydro-15-Keto-16,16-Difluoro-Pge1; Amitiza

Brief Introduction

Lubiprostone is a localized chloride channel activator, which can selectively activate the type 2 chloride channel (CIC-2) located on the lumen cell membrane at the tip of gastrointestinal epithelium, increase the secretion of intestinal fluid and intestinal motility, so as to increase defecation, reduce the symptoms of chronic idiopathic constipation, and do not change the concentration of sodium and potassium in plasma.

Suppliers

Shanghai Synovar & Lab Co., Ltd.

CNY 5 Million

70596m²

50-100 People

CRO CRO

Product Photo	Specification	Grade	Max Capacity	Certificates	Package

	99.0%	Pharm Grade	-	-	25kg / Fibre Drum

Main products:

Lubiprostone /Alfacalcidol /Isavuconazole /Carboprost Tromethamine /Calcidiol /Latanoprost /Dorzolamide /Bimatoprost

Pimecrolimus

CAS:137071-32-0

Molecular Formula:C43H68ClNO11

Alias

More Information

Elidel,Sdz-Asm-981; 33-Epi-33-Chloro-Fr 520; 33-Epi-Chloro-33-Desoxy-Ascomycin; 15,19-Epoxy-3H-Pyrido(2,1-C)(1,4)Oxaazacyclotricosine-1,7,20,21(4H,23H)-Tetrone, 3-((1E)-2-((1R,3R,4S)-4-Chloro-3-Methoxycyclohexyl)-1-Methylethenyl)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-Hexadecahydro-5,19-Dihydroxy-14,16-Dimethoxy-4,10,12,18-Tetramethyl-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26As)-; 15,19-Epoxy-3H-Pyrido(2,1-C)(1,4)Oxaazacyclotricosine-1,7,20,21(4H,23H)-Tetrone, 3-(2-(4-Chloro-3-Methoxycyclohexyl)-1-Methylethenyl)-8-Ethyl-, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-Hexadecahydro-5,19-Dihydroxy-14,16-

Brief Introduction

Pimecrolimus is a new immunosuppressant. 1% pimecrolimus cream has better skin permeability and low degree of percutaneous absorption, no systemic immunosuppression and no side effects of long-term external hormone. At present, it is used for eczema, dermatitis, vitiligo, seborrheic dermatitis and other skin diseases, showing good results and less adverse reactions.

Suppliers

Brightgene Bio-Medical Technology Co., Ltd.

CNY 410 Million

24642m²

100-500 People

Manufacturing Manufacturing

Product Photo	Specification	Grade	Max Capacity	Certificates	Package

	≥99.0%	Pharm Grade	-	-	5kg / BOTTLE

Main products:

Pimecrolimus /Obeticholic Acid /Tebipenem Pivoxil /Laninamivir Octanoate /Dienogest /Carboprost Tromethamine /Fish Oil /Eldecalcitol /Oseltamivir Phosphate /Sugammadex /Spinosyn D /Entecavir

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