Pharmaceutical Raw Materials

Proligestone is a derivative of 17α-Hydroxy Progesterone, which is a metabolite of Progesterone, a steroid hormone produced by the corpus luteum. Proligestone maintains the ability to affect the hypothalmic-pituitary-adrenocortical axis and glucose homeostasis.

Cineperate, western medicine name. The commonly used dosage form is injection. It is used for cerebrovascular diseases, cerebral arteriosclerosis, transient ischemic attack, cerebral thrombosis, cerebral embolism, postoperative recovery period of brain injury, sequelae of cerebral hemorrhage and sequelae of brain injury. Coronary heart disease and angina pectoris, if used for myocardial infarction, should be combined with relevant drug comprehensive treatment; It can also be used for peripheral vascular disease, such as lower extremity atherosclerosis, thromboangiitis obliterans, arteritis, Raynaud's disease, ophthalmology, Department of ENT disease, retinal arteriosclerosis, obstruction, ischemia induced ophthalmopathy, cochlear vestibular dysfunction caused by ischemia, sudden deafness, tinnitus, peripheral vascular disease caused by diabetes and microcirculation disturbance.

Alfaxalone (INN, JAN), also known as alphaxalone or alphaxolone (BAN), is a neuroactive steroid and general anaesthetic. It is used in veterinary practice under the trade name Alfaxan, and is licensed for use in both dogs and cats. Along with alfadolone, it is also one of the constituents of anesthetic drug mixture althesin. Unlike some of its predecessors alfaxalone is not associated with histamine release and anaphylaxis.; A study 1987 found the primary mechanism for the anaesthetic action of alfaxalone to be modulation of neuronal cell membrane chloride ion transport, induced by binding of alfaxalone to GABAA cell surface receptors. A 1994 study found that alfaxalone binds to a different region of this receptor than the benzodiazepines. These benzodiazepine-insensitive GABAA receptors are located extrasynaptically and are responsible for tonic inhibition. The occurrence of tonic GABAA inhibition coincides with the expression of relatively rare receptor subunits, particularly the α4, α6, and δ subunits, and as a rule of thumb, δ subunit-containing receptors are extrasynaptic. Alfaxalone is metabolised rapidly in the liver. It has a very short plasma elimination half-life in dogs and cats.

It can be used as an intermediate of cilodoxin.

Delta(9)-tetrahydrocannabinolic acid is a diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant. It has a role as an anti-inflammatory agent, a neuroprotective agent, a biomarker and a metabolite. It is a diterpenoid, a benzochromene, a hydroxy monocarboxylic acid, a polyketide and a phytocannabinoid. It is a conjugate acid of a Delta(9)-tetrahydrocannabinolate.