Pharmaceutical Raw Materials

This product is used as medicine raw material and organic synthesis.

Since probenecid is almost insoluble in water, when combined with penicillins for injection to form a compound injection, probenecid needs to be transformed into water-soluble salts, usually into water-soluble probenecid sodium. Probenecid sodium and probenecid potassium and β- The compound injection composed of lactam antibiotics and its application can reduce the content in the compound β- The dosage of lactam antibiotics can effectively reduce the occurrence and development of bacterial drug resistance caused by ultra-high dose antibiotics; It can also save antibiotic resources and reduce the abuse of antibiotics; Probenecid sodium (potassium) and β- Lactam antibiotics include penicillin antibiotics and cephalosporin antibiotics, which are composed of powder injection K and lyophilized powder injection β- Lactam antibiotics were injected intravenously or intravenously at the same time. Can effectively extend β- The half-life (T1 / 2) of lactam antibiotics can increase the area under the curve (AUC), eliminate the hemolysis of probenecid sodium (potassium), protect the safety of probenecid sodium (potassium) in human body, and can enter human body safely and effectively as a new compound preparation through intravenous route; By probenecid sodium (potassium) and β- Because the compound injection composed of lactam antibiotics directly enters the blood circulation and is completely absorbed by the human body, it can quickly reach the peak, act quickly and have more remarkable curative effect.

Proligestone is a derivative of 17α-Hydroxy Progesterone, which is a metabolite of Progesterone, a steroid hormone produced by the corpus luteum. Proligestone maintains the ability to affect the hypothalmic-pituitary-adrenocortical axis and glucose homeostasis.

Cineperate, western medicine name. The commonly used dosage form is injection. It is used for cerebrovascular diseases, cerebral arteriosclerosis, transient ischemic attack, cerebral thrombosis, cerebral embolism, postoperative recovery period of brain injury, sequelae of cerebral hemorrhage and sequelae of brain injury. Coronary heart disease and angina pectoris, if used for myocardial infarction, should be combined with relevant drug comprehensive treatment; It can also be used for peripheral vascular disease, such as lower extremity atherosclerosis, thromboangiitis obliterans, arteritis, Raynaud's disease, ophthalmology, Department of ENT disease, retinal arteriosclerosis, obstruction, ischemia induced ophthalmopathy, cochlear vestibular dysfunction caused by ischemia, sudden deafness, tinnitus, peripheral vascular disease caused by diabetes and microcirculation disturbance.

Alfaxalone (INN, JAN), also known as alphaxalone or alphaxolone (BAN), is a neuroactive steroid and general anaesthetic. It is used in veterinary practice under the trade name Alfaxan, and is licensed for use in both dogs and cats. Along with alfadolone, it is also one of the constituents of anesthetic drug mixture althesin. Unlike some of its predecessors alfaxalone is not associated with histamine release and anaphylaxis.; A study 1987 found the primary mechanism for the anaesthetic action of alfaxalone to be modulation of neuronal cell membrane chloride ion transport, induced by binding of alfaxalone to GABAA cell surface receptors. A 1994 study found that alfaxalone binds to a different region of this receptor than the benzodiazepines. These benzodiazepine-insensitive GABAA receptors are located extrasynaptically and are responsible for tonic inhibition. The occurrence of tonic GABAA inhibition coincides with the expression of relatively rare receptor subunits, particularly the α4, α6, and δ subunits, and as a rule of thumb, δ subunit-containing receptors are extrasynaptic. Alfaxalone is metabolised rapidly in the liver. It has a very short plasma elimination half-life in dogs and cats.