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Kgt-1681; Remogliflozin Etabonate; Unii-Tr0Qt6Qsul; Remogliflozin Etabonate (Usan/Inn); Gsk-189075; Tr0Qt6Qsul
Brief Introduction
Remogliflozin Etabonate is an orally available prodrug of remogliflozin, a benzylpyrazole glucoside-based inhibitor of renal sodium-glucose co-transporter subtype 2 (SGLT2) with antihyperglycemic activity. Upon administration and absorption, the inactive prodrug is converted to its active form remogliflozin and acts selectively on the sodium-glucose co-transporter subtype 2 (SGLT2).
CAS:4429-63-4
Molecular Formula:C21H24N2O2
Aspidospermidine-3-Carboxylicacid,2,3,6,7-Tetrahydro-,Methylester,(5-Alpha; Aspidospermidine-3-Carboxylic Acid, 2,3,6,7-Tetradehydro-, Methyl Ester, (5Alpha,12Beta,19Alpha)-
Brief Introduction
This product is a plant extract. It is used as a medical raw material and has the effect of reducing blood pressure. Used for content determination / identification / pharmacological experiment, etc.
CAS:4430-31-3
Molecular Formula:C9H14O2
Octahydrocoumarin; Bicyclononalactone; Octahydrochromen-2-One; Octahydro-2H-Chromen-2-One; Octahydro(2H)-1-Benzopyran-2-One; 2H-1-Benzopyran-2-One,Octahydro; Cyclohexyl Lactone; 1-Oxadecal-2-One; 3,4,4A,5,6,7,8,8A-Octahydrochromen-2-One; 2H-1-Benzopyran-2-One, Octahydro-
Brief Introduction
This product is a permitted edible spice and can be used as food additive.
Hdp-Cidofovir; 1-O-Hexadecylpropanediol-Cdv; Hdp-Hpmpc; Cmx001; Hdp-Cdv; Brincidofovir; Hexadecyloxypropyl-Cidofovir
Brief Introduction
Brincidofovir 是一种烷氧基烷基酯前药,含有合成的无环核苷单磷酸类似物西多福韦,通过其膦酸酯基团与脂质3-十六烷氧基-1-丙醇相连,对双链 DNA 病毒具有抗病毒活性。口服给药后,brincidofovir 穿过肠壁并穿透目标病毒感染细胞,然后被裂解为游离的抗病毒药物西多福韦。反过来,西多福韦被丙酮酸激酶磷酸化为其活性代谢物西多福韦二磷酸。西多福韦二磷酸与核苷酸结构相似,与脱氧胞嘧啶 5-三磷酸 ( dCTP )竞争病毒 DNA 聚合酶,并整合到不断增长的病毒 DNA 链中。因此,它可以防止 DNA 进一步聚合并破坏病毒的 DNA 复制。与静脉内给予的西多福韦相比,十六烷氧基丙基-西多福韦显示出更好的口服生物利用度、更低的毒性和增强的细胞渗透。
CAS:446-72-0
Molecular Formula:C15H10O5
4’,5,7-Trihydroxy-Isoflavon; 5,7-Dihydroxy-3-(4-Hydroxyphenyl)-4H-1-Benzopyran-4-On; Genisteol; Prunetol; 5,7-Dihydroxy-3-(4-Hydroxyphenyl)-4H-Chromen-4-One
Brief Introduction
An isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 phase arrest in human and murine cell lines. Additionally, genistein has antihelmintic activity. It has been determined to be the active ingredient in Felmingia vestita, which is a plant traditionally used against worms. It has shown to be effective in the treatment of common liver fluke, pork trematode and poultry cestode. Further, genistein is a phytoestrogen which has selective estrogen receptor modulator properties. It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women. Natural sources of genistein include tofu, fava beans, soybeans, kudzu, and lupin.
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