Pamedon; (+-)-4,4-Diphenyl-6-Piperidino-Heptan-3-One; Fenpidon; Dipypanone; 4,4-Diphenyl-6-Piperidino-Heptan-3-On; Pipadone; 4,4-Di(Phenyl)-6-Piperidin-1-Ylheptan-3-One; Piperidylamidone

Brief Introduction

Dipipanone is a DEA Schedule I controlled substance. Substances in the DEA Schedule I have no currently accepted medical use in the United States, a lack of accepted safety for use under medical supervision, and a high potential for abuse.

2-[2-(Diethylamino)Ethoxy]Ethyl 2-Ethyl-2-Phenylbutanoate

MSDS

CAS:468-61-1

Molecular Formula:C20H33NO3

Alias

More Information

Oxeladina [Inn-Spanish]; 2-Ethyl-2-Phenyl-Butyric Acid-[2-(2-Diethylamino-Ethoxy)-Ethyl Ester]; Einecs 207-412-1; Oxeladin; 2-Aethyl-2-Phenyl-Buttersaeure-[2-(2-Diaethylamino-Aethoxy)-Aethylester]; Oxeladinum [Inn-Latin]; Oxeladine [Inn-French]; Oxeladina; 2-(2-Diethylaminoethoxy)Ethyl 2-Ethyl-2-Phenylbutyrate; Oxeladinum; Oxeladine

Brief Introduction

Oxeladin is a cough suppressant. It is a highly potent and effective drug used to treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is free of risk of dependence or addiction. Oxeladin has none of the side effects (such as hypnosis, respiratory depression, tolerance, constipation and analgesia) which are present when common antitussives, such as codeine and its derivatives, are used. It may be used at every age, as well as in patients with heart disease, since it has a high level of safety and a great selectivity to act on the bulbar centre of cough.

Doxylamine

MSDS

CAS:469-21-6

Molecular Formula:C17H22N2O

Alias

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Dossilamina; Doxilamina; Doxilminio; Doxylaminum; N,N-Dimethyl-2-(1-Phenyl-1-Pyridin-2-Ylethoxy)Ethanamine

Brief Introduction

Doxylamine is a first-generation antihistamine, first reported in 1949. It can be used by itself as a short-term sedative and in combination with other drugs to provide night-time allergy and cold relief. Doxylamine is also used in combination with the analgesics paracetamol (acetaminophen) and codeine as an analgesic/calmative preparation, and is prescribed in combination with vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women. Its fetal safety is “A” in Briggs’ Reference Guide to Foetal and Neonatal Risk.

Dextropropoxyphene

MSDS

CAS:469-62-5

Molecular Formula:C22H29NO2

Alias

More Information

Dextropropoxifeno; [(2S,3R)-4-(Dimethylamino)-3-Methyl-1,2-Diphenylbutan-2-Yl] Propanoate; Destropropossifene; Dextroproxifeno; Dextropropoxyphenum; D-Propoxyphene; Propoxyphene; Algafan; Darvon; Dextropropoxyphen

Brief Introduction

Propoxyphene is the d-isomer of synthetic diphenyl propionate derivative propoxyphene, with narcotic analgesic effect. This agent mimics the effects of the endogenous opiate dextropropoxyphene, by binding to mu receptors located throughout the central nervous system. The binding results in GTP to GDP exchanges on the mu-G-protein complex, by which effector adenylate cyclase is inactivated thereby decreasing intracellular cAMP. This, in turn, inhibits the release of various nociceptive neurotransmitters, such as substance P, gamma-aminobutyric acid (GABA), dopamine, acetylcholine, noradrenaline, vasopressin, and somatostatin. In addition, dextropropoxyphene closes N-type voltage-gated calcium channels and opens calcium-dependent inwardly rectifying potassium channels. This results in hyperpolarization, thereby reducing neuronal excitability, which further decreases the perception of pain.

1-[4-(3-Hydroxyphenyl)-1-Methylpiperidin-4-Yl]Propan-1-One

MSDS

CAS:469-79-4

Molecular Formula:C15H21NO2

Alias

More Information

Cetobemidon; Ketobemidon; Cliradon; 1-[4-(3-Hydroxyphenyl)-1-Methyl-4-Piperidyl]-1-Propanone; Ketobemidone; Ciba 7115; Cetobemidona; 1-[4-(3-Hydroxy-Phenyl)-1-Methyl-[4]Piperidyl]-Propan-1-One; Cetobemidone; Cliradone; 1-[4-(3-Hydroxy-Phenyl)-1-Methyl-[4]Piperidyl]-Propan-1-On; Ketorax; A 21 Lundbeck; Cymidon

Brief Introduction

酮贝米酮是一种强效的阿片类镇痛剂。它还具有一些NMDA拮抗剂特性。这使得它对某些对其他阿片类药物反应不佳的疼痛很有用。最常提及的镇痛剂量均衡比是 25 mg氢溴酸酮贝米酮对 60 mg盐酸吗啡或硫酸盐和大约 8 mg 酮贝米酮注射液。

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