Pharmaceutical Raw Materials

D-Glucose pentaacetate was reported to stimulate insulin release in rat pancreatic islets. Only α-D-glucose pentaacetate caused an immediate increase in insulin output. The β-anomer of D-glucose pentaacetate first transiently inhibited insulin release, this initial effect being followed by a secondary rise in secretory rate.

4-dimethylaminobenzoic acid is an organic intermediate, which can be methylated from ethyl p-aminobenzoate to ethyl 4-dimethylaminobenzoate, and then hydrolyzed to ethyl 4-dimethylaminobenzoate; Or it is obtained by coupling p-chlorobenzoic acid with dimethylamine. It is used in intermediates of fine chemicals, synthesis of high-efficiency photosensitive materials, photoelectric conversion devices, coatings and UV radiation.   As an important intermediate of photosensitizer, coating and dye intermediate.

Betaxolol Hydrochloride is the hydrochloride salt form of betaxolol, a beta-1-selective adrenergic receptor antagonist without intrinsic sympathomimetic activity. Betaxolol hydrochloride acts on the heart and circulatory system and decreases cardiac contractility and rate, thereby reducing cardiac output. When applied topically in the eye, it lowers intraocular pressure by reducing aqueous humor secretion.

The effect of non depolarizing muscle relaxants was 2.5 times of that of tubuline, but the duration of action was short. It is used in various surgical operations, especially tracheal intubation and cesarean section.

Propacetamol is a precursor of acetaminophen. Its hydrochloride can be hydrolyzed by Plasma Esterase to produce free acetaminophen after it is injected into human body by intravenous injection or intramuscular injection. It overcomes the instability of acetaminophen and has the pharmacological effects of antipyretic and analgesic. The analgesic effect of propacetamol is similar to that of opioids, but it has no inhibitory effect on the central nervous system, so it does not cause adverse reactions such as respiratory depression, nausea and vomiting, and has the characteristics of non addiction and high analgesic effect; As a new type of non steroidal antipyretic analgesic, its mechanism of action is different from that of traditional non steroidal drugs. It has less adverse reactions in kidney, gastrointestinal tract and blood. Its prescription is simple and safe, so it is worthy of clinical application.