((2-(6-Amino-9H-Purin-9-Yl)Ethoxy)Methyl)Phosphonic Acid; Pmea; Treatment Adefovir; Tenofovir Desmethyl Impurity; 2-(6-Amino-9H-Purin-; Adefovir Dipivox (Pmea); [[2-(6-Amino-9H-Purin-9-Yl)Ethoxy]; Methyl]Phosponic Acid; P-[[2-(6-Amino-9H-Purin-9-Yl)Ethoxy]Methyl]Phosphonic Acid; Adefovir(Pmea)

Brief Introduction

Adefovir is a acyclic nucleoside analogue of adenosine monophosphate. It is a new type of anti HBV drug. It is used in the form of the former drug A Duff Vee ester, and belongs to adenine nucleoside. Under the action of cell kinase, Adefovir is phosphorylated to an active metabolite, namely adefovir diphosphate. Adefovir diphosphate inhibits HBV DNA polymerase (reverse transcriptase) in two ways. One is that it competes with the natural substrate deoxyadenosine triphosphate, and the other is that it causes DNA strand elongation and termination after integration into virus DNA. Therefore, Adefovir is mainly used for the treatment of adult chronic hepatitis B patients with evidence of active replication of hepatitis B virus, continuous increase of serum amino acid transferase (ATL or AST), or liver tissue active lesions with liver function compensation.

Cefeprime Dihydrochloride

CAS:107648-80-6

Molecular Formula:C19H26Cl2N6O5S2

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Pyrrolidinium,1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-Thiazolyl)-2-(Methoxyimino)Acetyl]Amino]-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-,Chloride,Hydrochloride (1:1:1; 1-[[(6R,7R)-7-[2-(2-Amino-4-Thiazolyl)-2-(Z-Methoxyimino)-Acetamido]-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-Pyrrolidinium Chloride,Monohydrochloride; L-[[(6R,7R)-7-[2-(2-Amino-4-Thiazolyl)-Glyoxylamido]-2-Carboxy-8-Oxo-5-Thia-L-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-Pyrrolidinium Chloride; 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-Thiazolyl)(Methoxyimino)Acetyl]Amino]-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-Pyrrolidinium Chloride Hydrochloride; Cefepime Dihydrochloride; (6R,7R)-7-[[(2E)-2-(2-Amino-1,3-Thiazol-4-Yl)-2-Methoxyiminoacetyl]Amino]-3-[(1-Methylpyrrolidin-1-Ium-1-Yl)Methyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid Chloride Hydrochloride; Cefepime Hcl Sterile Powder; Cefepime Hcl; Cefepime Hydrochloric; Pyrrolidinium,1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-Thiazolyl)-2-(Me

Brief Introduction

For the treatment of a variety of bacterial infections, including severe infections.

2-((1-(1-(4-Fluorobenzyl)-1H-Benzo[D]Imidazol-2-Yl)Piperidin-4-Yl)(Methyl)Amino)Pyrimidin-4(1H)-One

CAS:108612-45-9

Molecular Formula:C24H25FN6O

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Mizolastine; Mizollen; Zolistan; Sl 85.0324

Brief Introduction

Mizolastine is an antihistamine, also known as mizolastine. It not only has strong antihistamine effect, but also can inhibit other inflammatory transmitters, such as inhibiting the production of leukotrienes and reducing edema. Therefore, in theory, mizolastine not only has antihistamine and antiallergic effects, but also has anti-inflammatory activity. It is the preferred drug for the treatment of acute urticaria. It takes effect significantly faster than other antihistamines. After 1 ~ 3 hours, the number of wind masses is reduced, the degree of pruritus is reduced, and the maintenance time is long, up to 24 hours. At present, it is mainly used to treat skin allergy symptoms such as urticaria, seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis in adults or children over 12 years old.

1H-Pyrrole

CAS:109-97-7

Molecular Formula:C4H5N

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Monopyrrole; Parzate; Divinylenimine; Pyrroline; 1H-Pyrrole; Pyrrol; Fema 3386; Pyrrole; Pyrrhol; Azole; Azole,Divinylenimine,Imidole; Imidole

Brief Introduction

Pyrrole and its homologues are mainly found in bone tar, but few in coal tar. Pyrrole can be obtained by fractionation of bone tar; Or it can be treated with dilute alkali and then purified by fractionation after acidification. It is a five membered heterocyclic compound with one aza atom and its molecular formula is C4H5N. It is also used in organic synthesis and pharmaceutical industry. Mainly used as polyester fiber spinning solvent. It is also used as metal preservative, curing agent of epoxy resin, catalyst for olefin polymerization and raw material for pharmaceutical industry. It is also used as a photosensitizer.

Pamidronate Disodium Pentahydrate

CAS:109552-15-0

Molecular Formula:C3H19NNa2O12P2

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Pamidronate Disodium; Disodium Pamidronate; Disodium(3-Amino-1-Hydroxypropylidene)Bisphosphonatepentahydrate; Disodiumdihydrogen(3-Amino-1-Hydroxypropylidene)Diphosphatepentahydrate; Phosphonicacid,(3-Amino-1-Hydroxypropylidene)Bis-,Disodiumsalt,Pentahydrat; Aminomux; Aredia; Gcp-23339A; Disodium 3-Amino-1-Hydroxy-Propylidenebisphosphonate; 3-Amino-1-Hydroxypropylidene-Bisphosphonic Acid, 2Na

Brief Introduction

Pamidronate disodium is a potent osteoclast bone resorption inhibitor. In vitro, it binds closely to hydroxyapatite crystals and inhibits their formation and dissolution. In vivo, it can combine with bone minerals and inhibit osteoclastic bone resorption. Pamidronate can inhibit the attachment of osteoclast precursors to bone and inhibit their transformation into mature and functional osteoclasts. Both in vivo and in vitro, the local and direct anti bone resorption effect of bone bound bisphosphonates is the main mode of action. Experimental studies have shown that pamidronate disodium can inhibit tumor induced osteolysis before or at the same time of tumor cell inoculation or transplantation. Its inhibitory effect on hypercalcemia induced by tumor is shown by the following biochemical changes: the decrease of serum calcium and the secondary reduction of excretion of calcium, phosphate and hydroxyproline in urine.

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