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CAS:107133-36-8
Molecular Formula:C23H43N3O5
Alias
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Aceon; Perindopril Tert-Butylamine; Prestarium; Perindopril T-Butylamine Salt; Unii-1964X464Oj; Butylaminiperindopril; Perinodopril; Coversum; Perindoril; Prindopril Api; (2S,3As,7As)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)Butyl]Amino]-1-Oxopropyl]Octahydro-1H-Indole-2-Carboxylic Acid Tert-Butylamine Salt; (2S,3As,7As)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)Butyl]Amino]-1-Oxopropyl]Octahydro-1H-Indole-2-Carboxylic Acid 2-Methyl-2-Propanamine
Brief Introduction
Perindopril is an inhibitor of an enzyme (angiotensin converting enzyme) that converts angiotensin I to angiotensin II. This kind of invertase or kinase is a kind of peptidolytic enzyme. It can convert angiotensin I into angiotensin II, which is used to constrict blood vessels. It can also degrade bradykinin, which is used to dilate blood vessels, into inactive heptapeptide. Inhibition of angiotensin converting enzyme results in a decrease of angiotensin II in plasma, which leads to an increase in plasma renin activity (by inhibiting the negative feedback of renin release) and a decrease in aldosterone secretion. Because angiotensin-converting enzyme inactivates bradykinin, inhibition of angiotensin-converting enzyme can also increase the activity of circulating and local kallikrein kinin system (and thus prostaglandin system). This mechanism may be related to the effect of angiotensin converting enzyme inhibitors on lowering blood pressure, and may also be related to some side effects (such as cough). Perindopril acts through its active metabolite perindoprila.
CAS:107648-80-6
Molecular Formula:C19H26Cl2N6O5S2
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Pyrrolidinium,1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-Thiazolyl)-2-(Methoxyimino)Acetyl]Amino]-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-,Chloride,Hydrochloride (1:1:1; 1-[[(6R,7R)-7-[2-(2-Amino-4-Thiazolyl)-2-(Z-Methoxyimino)-Acetamido]-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-Pyrrolidinium Chloride,Monohydrochloride; L-[[(6R,7R)-7-[2-(2-Amino-4-Thiazolyl)-Glyoxylamido]-2-Carboxy-8-Oxo-5-Thia-L-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-Pyrrolidinium Chloride; 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-Thiazolyl)(Methoxyimino)Acetyl]Amino]-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-Pyrrolidinium Chloride Hydrochloride; Cefepime Dihydrochloride; (6R,7R)-7-[[(2E)-2-(2-Amino-1,3-Thiazol-4-Yl)-2-Methoxyiminoacetyl]Amino]-3-[(1-Methylpyrrolidin-1-Ium-1-Yl)Methyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid Chloride Hydrochloride; Cefepime Hcl Sterile Powder; Cefepime Hcl; Cefepime Hydrochloric; Pyrrolidinium,1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-Thiazolyl)-2-(Me
Brief Introduction
For the treatment of a variety of bacterial infections, including severe infections.
CAS:108612-45-9
Molecular Formula:C24H25FN6O
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Mizolastine; Mizollen; Zolistan; Sl 85.0324
Brief Introduction
Mizolastine is an antihistamine, also known as mizolastine. It not only has strong antihistamine effect, but also can inhibit other inflammatory transmitters, such as inhibiting the production of leukotrienes and reducing edema. Therefore, in theory, mizolastine not only has antihistamine and antiallergic effects, but also has anti-inflammatory activity. It is the preferred drug for the treatment of acute urticaria. It takes effect significantly faster than other antihistamines. After 1 ~ 3 hours, the number of wind masses is reduced, the degree of pruritus is reduced, and the maintenance time is long, up to 24 hours. At present, it is mainly used to treat skin allergy symptoms such as urticaria, seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis in adults or children over 12 years old.
CAS:109-97-7
Molecular Formula:C4H5N
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Monopyrrole; Parzate; Divinylenimine; Pyrroline; 1H-Pyrrole; Pyrrol; Fema 3386; Pyrrole; Pyrrhol; Azole; Azole,Divinylenimine,Imidole; Imidole
Brief Introduction
Pyrrole and its homologues are mainly found in bone tar, but few in coal tar. Pyrrole can be obtained by fractionation of bone tar; Or it can be treated with dilute alkali and then purified by fractionation after acidification. It is a five membered heterocyclic compound with one aza atom and its molecular formula is C4H5N. It is also used in organic synthesis and pharmaceutical industry. Mainly used as polyester fiber spinning solvent. It is also used as metal preservative, curing agent of epoxy resin, catalyst for olefin polymerization and raw material for pharmaceutical industry. It is also used as a photosensitizer.
CAS:109552-15-0
Molecular Formula:C3H19NNa2O12P2
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Pamidronate Disodium; Disodium Pamidronate; Disodium(3-Amino-1-Hydroxypropylidene)Bisphosphonatepentahydrate; Disodiumdihydrogen(3-Amino-1-Hydroxypropylidene)Diphosphatepentahydrate; Phosphonicacid,(3-Amino-1-Hydroxypropylidene)Bis-,Disodiumsalt,Pentahydrat; Aminomux; Aredia; Gcp-23339A; Disodium 3-Amino-1-Hydroxy-Propylidenebisphosphonate; 3-Amino-1-Hydroxypropylidene-Bisphosphonic Acid, 2Na
Brief Introduction
Pamidronate disodium is a potent osteoclast bone resorption inhibitor. In vitro, it binds closely to hydroxyapatite crystals and inhibits their formation and dissolution. In vivo, it can combine with bone minerals and inhibit osteoclastic bone resorption. Pamidronate can inhibit the attachment of osteoclast precursors to bone and inhibit their transformation into mature and functional osteoclasts. Both in vivo and in vitro, the local and direct anti bone resorption effect of bone bound bisphosphonates is the main mode of action. Experimental studies have shown that pamidronate disodium can inhibit tumor induced osteolysis before or at the same time of tumor cell inoculation or transplantation. Its inhibitory effect on hypercalcemia induced by tumor is shown by the following biochemical changes: the decrease of serum calcium and the secondary reduction of excretion of calcium, phosphate and hydroxyproline in urine.
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