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Jiangsu Hansyn Pharmaceutical Co., Ltd.

22 YRS

Jiangsu, China

CNY 120 Million

144522 m²

100-500 people

Main Products: Florfenicol / Efinaconazole / Posaconazole / Sitagliptin / Ezetimibe / Thiamphenicol

Jiangsu, China

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Ezetimibe / CAS 163222-33-1

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Ezetimibe

English Name: ezetimibe

CAS No.: 163222-33-1

Molecular formula: C24H21F2NO3

Molecular weight: 409.43

EINECS No.: 682-606-0

Melting point: 164-166 ° C

Boiling point: 654.9 ± 55.0 ° C (predicted) '

Density: 1.334 ± 0.06 g / cm3 (predicted)

Application:ezetimibe is a white crystalline powder, very soluble in ethanol, methanol and acetone, insoluble in water, with a melting point of about 163 ℃ and stable at room temperature.Ezetimibe only acts on the small intestine and reduces the transport of intestinal cholesterol to the liver and its storage by inhibiting the absorption of cholesterol; It can enhance the clearance of cholesterol in the blood and reduce the level of plasma cholesterol.

Typical Properties

Ezetimibe is a white crystalline powder, very soluble in ethanol, methanol and acetone, insoluble in water, with a melting point of about 163 ℃ and stable at room temperature. Ezetimibe only acts on the small intestine and reduces the transport of intestinal cholesterol to the liver and its storage by inhibiting the absorption of cholesterol; It can enhance the clearance of cholesterol in the blood and reduce the level of plasma cholesterol.

CAS No.

163222-33-1

Formula

C24H21F2NO3

Molecular Mass

409.42500

Exact Mass

409.14900

PSA

60.77000

Logp

4.95330

IUPAC

(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one

SMILES

C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O

Matter Classification

organic

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