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Jiangsu Hansyn Pharmaceutical Co., Ltd.

22 YRS

Jiangsu, China

CNY 120 Million

144522 m²

100-500 people

Main Products: Florfenicol / Efinaconazole / Posaconazole / Sitagliptin / Ezetimibe / Thiamphenicol

Jiangsu, China

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Posaconazole / CAS 171228-49-2

EU-GMP /DMF in submission

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Posaconazole

English Name: posaconazole

CAS No.: 171228-49-2

Molecular formula: C37H42F2N8O4

Molecular weight: 700.78

EINECS No.: 682-747-8

Melting point: 170-172 ℃

Boiling point: 850.7 ± 75.0 ° C (predicted)

Density: 1.36 ± 0.1 g / cm3 (predicted)

Flash point: 9 ℃

Use: posaconazole is used in patients with invasive aspergillosis refractory to amphotericin B or itraconazole or patients who cannot tolerate the treatment of these drugs. Clinically, it can be used for the treatment of aspergillosis, zygomycosis and Fusarium disease, and can also be used for the treatment of some fluconazole resistant Candida infections.

Typical Properties

Posaconazole is used in patients with invasive aspergillosis refractory to amphotericin B or itraconazole or in patients who cannot tolerate treatment with these agents.It is clinically useful in the treatment of aspergillosis, zygomycosis and sickle cell disease, but also in the treatment of some fluconazole resistant Candida infections.

CAS No.

171228-49-2

Formula

C37H42F2N8O4

Molecular Mass

700.77700

Exact Mass

700.33000

PSA

115.70000

Logp

4.70320

IUPAC

4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one

SMILES

CCC(C(C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5CC(OC5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F

Matter Classification

organic

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