DMF
content: ≥ 99.9%
performance:
The relative density is 0.9445 (25 ℃). Melting point - 61 ℃. Boiling point 152.8 ℃. Flash point 57.78 ℃. Vapor density 2.51. Vapor pressure 0.49kpa (3.7mmhg25 ℃). The spontaneous combustion point is 445 ℃. Refractive index 1.42817, solubility parameter δ= 12.1。 The explosion limit of steam and air mixture is 2.2 ~ 15.2%. It is miscible with water and usually organic solvents, mixed with petroleum ether and layered. In case of open fire and high heat, it can cause combustion and explosion. It can react violently with concentrated sulfuric acid, fuming nitric acid and even explode.
main purpose:
It is mainly used as industrial solvent, in the pharmaceutical industry for the production of vitamins and hormones, and also for the manufacture of Chlordimeform.
[packaging, storage and transportation]
Packing method: ordinary wooden case outside ampoule bottle; Threaded glass bottles, iron cap crimped glass bottles, plastic bottles or ordinary wooden cases outside metal barrels (cans); Special tank car. It is forbidden to slip away during railway transportation. It is strictly prohibited to transport in bulk with wooden ships and cement ships.
emergency measures for leakage:
Quickly evacuate personnel from the leakage contaminated area to a safe area; Isolate the leakage contaminated area and restrict access; Cut off the fire source; It is recommended that emergency treatment personnel wear gas masks and general fire protective clothing or rubber protective clothing; Absorb with sand, vermiculite or other inert materials and transport to the waste treatment site for disposal; It can also be washed with a large amount of water and diluted into the wastewater system; In case of a large amount of leakage, build a dike or dig a pit for reception.
Dimethylformamide is a good organic solvent and widely used. In petrochemical industry, dimethylformamide can be used as gas absorbent to separate and refine gas. As a washing and curing agent in polyurethane industry, it is mainly used in wet synthetic leather production; As a solvent in acrylic fiber industry, it is mainly used in dry spinning production of acrylic fiber; In the electronic industry as tinning parts of quenching and circuit board cleaning, etc; Other industries include carriers of dangerous gases, solvents for drug crystallization, adhesives, etc. In organic reactions, dimethylformamide is not only widely used as a solvent, but also an important intermediate in organic synthesis. It can be used to produce Chlordimeform in pesticide industry; In the pharmaceutical industry, it can be used for the synthesis of iodamine pyrimidine, doxycycline, cortisone, vitamin B6, iodoside, qupinjing, thiadiazine, n-formylsarcoma lysin, antineoplastic acid, methoxyaryl mustard, benazepril, cyclohexylnitrosourea, furafluorouracil, hemostatic acid, betamethasone, megestrol, danvita, chlorphenamine and sulfonamides. Dimethylformamide plays a catalytic role in hydrogenation, dehydrogenation, dehydration and dehydrohalogenation, which reduces the reaction temperature and improves the purity of the product.
IUPAC
N,N-dimethylformamide