Dimethylformamide
【 Appearance and shape 】 colourless, pale amine smelling liquid.
【 Danger characteristics 】 experience bright fire, high heat can cause combustion explosion. Can react vigorously with concentrated sulfuric acid, nitric acid and even explosion.
【 Method of first aid 】
Skin to skin contact: remove contaminated clothing immediately and rinse with copious flow of clean water for at least 15 minutes. Seek medical attention.
Eye contact: lift the eyelid immediately and rinse thoroughly with copious flow of clear water or saline for at least 15 minutes. Seek medical attention.
Inhalation: rapidly withdraw from site to air fresh. Maintain airway patency. Such as breathing difficulties, give oxygen. If breathing stops, take artificial respiration immediately and seek medical attention. Ingestion: rinse with water, give milk or egg white, and seek medical attention.
Fire fighting measures] method of fire suppression: start by cutting off all sources of fire and wearing gas masks and gloves. Rinse with water and the diluted effluent put into the waste water system.
【 emergency treatment 】
Personnel from the spill contaminated zone are rapidly evacuated to the containment zone and are isolated, with strict restrictions on access. Cut off the fire source. It is recommended that emergency responders wear self-contained positive pressure respirators. Do not come into direct contact with the leak. The source of leakage was cut as far as possible. Prevent restricted spaces such as inflow drains and floodways. Small leakage: adsorption or absorption with sandy soil or other nonflammable materials. It is also possible to spille the ground on soda ash, which is then rinsed with copious amounts of water, which is diluted and placed into the wastewater system. Gross leak: Construction of a peri - wall or burrow containment. Cover with foam, reduce vapor disasters. Spray like water to cool and dilute steam. Transfer by pump to within tank car or dedicated collector, recycling or transport to waste disposal site for disposal. Other protection: smoking, eating and drinking are prohibited at the work site.
Dimethylformamide is a good organic solvent and widely used. In petrochemical industry, dimethylformamide can be used as gas absorbent to separate and refine gas. As a washing and curing agent in polyurethane industry, it is mainly used in wet synthetic leather production; As a solvent in acrylic fiber industry, it is mainly used in dry spinning production of acrylic fiber; In the electronic industry as tinning parts of quenching and circuit board cleaning, etc; Other industries include carriers of dangerous gases, solvents for drug crystallization, adhesives, etc. In organic reactions, dimethylformamide is not only widely used as a solvent, but also an important intermediate in organic synthesis. It can be used to produce Chlordimeform in pesticide industry; In the pharmaceutical industry, it can be used for the synthesis of iodamine pyrimidine, doxycycline, cortisone, vitamin B6, iodoside, qupinjing, thiadiazine, n-formylsarcoma lysin, antineoplastic acid, methoxyaryl mustard, benazepril, cyclohexylnitrosourea, furafluorouracil, hemostatic acid, betamethasone, megestrol, danvita, chlorphenamine and sulfonamides. Dimethylformamide plays a catalytic role in hydrogenation, dehydrogenation, dehydration and dehydrohalogenation, which reduces the reaction temperature and improves the purity of the product.
IUPAC
N,N-dimethylformamide