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Hubei Biocause Heilen Phamaceutical Co., Ltd.

29 YRS

Hubei, China

CNY 180 Million

139860 m²

500-1000 people

Main Products: Torasemide / Ibuprofen / Dexibuprofen / Ibuprofen Lysinate / Granisetron Hydrochloride / Tropisetron Hydrochloride / Dolasetron Mesylate / Fludarabine Phosphate / Abiraterone / Azacytidine / Clofarabine / Atropine Sulfate / Hyoscyamine Sulfate / Milrinone / Flumazenil / Cladribine / Homatropine Methyl Bromide / Oxaprozin / Balsalazide Sodium

Hubei, China

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Azacytidine / CAS 320-67-2

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Azacitidine

Name in English: azacytidine

CAS number: 320-67-2

Molecular formula: C8H12N4O5

MW: 244.2

EINECS number: 206-280-2

Uses: antimetabolites. The primary indication is acute myeloid leukemia that is refractory to conventional therapy. It is also used for breast cancer, melanoma, bowel cancer, etc. Toxicities were mainly characterized by leukopenia, thrombocytopenia, and anemia.

Typical Properties

Antimetabolic drugs. The main indication is acute myeloid leukemia which is ineffective to conventional treatment. It is also used for breast cancer, melanoma, intestinal cancer and so on. The main manifestations of toxicity were leucopenia, thrombocytopenia and anemia. Nausea and vomiting are common adverse reactions. Symptoms can be improved by continuous infusion for a long time, or antiemetic agents can be used 24 to 48 hours before treatment. Other toxic effects were diarrhea, neuromuscular disorders, fever, hypotension and rash. The preparation is freshly prepared 3-4h before use.

CAS No.

320-67-2

Formula

C8H12N4O5

Molecular Mass

244.20500

Exact Mass

244.08100

PSA

143.72000

Logp

-2.58680

IUPAC

4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one

SMILES

C1=NC(=NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N

Matter Classification

organic

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