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Hubei Biocause Heilen Phamaceutical Co., Ltd.

29 YRS

Hubei, China

CNY 180 Million

139860 m²

500-1000 people

Main Products: Torasemide / Ibuprofen / Dexibuprofen / Ibuprofen Lysinate / Granisetron Hydrochloride / Tropisetron Hydrochloride / Dolasetron Mesylate / Fludarabine Phosphate / Abiraterone / Azacytidine / Clofarabine / Atropine Sulfate / Hyoscyamine Sulfate / Milrinone / Flumazenil / Cladribine / Homatropine Methyl Bromide / Oxaprozin / Balsalazide Sodium

Hubei, China

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Cladribine / CAS 4291-63-8

OVERVIEW

Uses

1,1-Cyclohexanediacetic Acid Mono Amide 1,1-Cyclohexanediacetic Acid Mono Amide

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Cladribine

Name in English: cladribine

CAS number: 4291-63-8

Molecular formula: C10H12ClN5O3

MW: 285.69

EINECS number: 636-978-6

Uses: as an adenosine deaminase resistant deoxyadenosine analog. For active hairy cell leukemia.

Typical Properties

Cladribine is a purine analogue and antineoplastic agent used primarily in the therapy of hairy cell leukemia. Cladribine is typically given intravenously daily for 7 days, usually as a single course, and has not been associated with serum enzyme elevations during therapy or with instances of clinically apparent acute liver injury with jaundice. Cladribine is 2'-Deoxyadenosine in which the hydrogen at position 2 on the purine ring has been substituted by chlorine. It inhibits the synthesis and repair of DNA, particularly in lymphocytes and monocytes, and is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including hairy-cell leukaemia and chronic lymphocytic leukaemia. It has a role as an antineoplastic agent and an immunosuppressive agent. It is a purine 2'-deoxyribonucleoside and an organochlorine compound.

CAS No.

4291-63-8

Formula

C10H12ClN5O3

Molecular Mass

285.68700

Exact Mass

285.06300

PSA

119.31000

Logp

0.28380

IUPAC

(2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

SMILES

C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=C(N=C32)Cl)N)CO)O

Matter Classification

organic

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