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Jinan Jinda Pharmaceutical Chemistry Co.,Ltd.
Jinan Jinda Pharmaceutical Chemistry Co.,Ltd.
32 YRS
Shandong, China
Main Products:
Nitrofurantoin / Nitrofurantoin Monohydrate / Tolperisone Hydrochloride / Nitrofurazone / Carprofen / Dantrolene Sodium / Haloperidol / Cyclandelate / Dipyridamole / Phenylbutazone / Feprazone / Foscarnet Sodium / 1-Aminohydantoin Hydrochloride
Shandong, China
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Haloperidol / CAS 52-86-8
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Haloperidol
Synonymous: 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-hydroxypiperidinium
CAS: 52-86-8
Structure:
Molecular formula: C21H23ClFNO2
Molecular weight: 375.87
Authentication code: H37022198
Specification: China Pharmacopoeia 2010
Appearance: White or almost white crystalline powder
Melting point: 149-153οC
Absorption coefficient: 338-360
Individual biggest impurity: ≤0.5%
Total impurities: ≤ 1.0%
Loss on drying: Not more than 0.5% (Vacuum at 60οC)
Residue on ignition: Not more than 0.1%
Assay: Not more than 98.5%
Application: Used for curing psychopathy, schizophrenia, and madness disease.
Typical Properties
Summary
This product is the most commonly used drug in butyryl benzene antipsychotics and is listed in the national catalogue of essential drugs. Antipsychotics, formerly known as strong tranquilizers, are mainly used to control schizophrenia and other diseases related to hallucinations, delusions, excitement, impulses and so on. Haloperidol is mainly used to resist mania and hallucinations in acute and chronic schizophrenia. It has a significant effect on controlling excitement and agitation, but it has no effect on depression and indifference in schizophrenia. The oral LD50 of rats was 165 mg / kg.
CAS No.
52-86-8
Formula
C21H23ClFNO2
Molecular Mass
375.86400
Exact Mass
375.14000
PSA
40.54000
Logp
4.36350
IUPAC
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
SMILES
C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Pharmaceutical Raw Materials
Chemical and Physical Properties
Melting Point
152 °C
Density
1.3 g/cm3
Boiling Point
529ºC
Appearance
White or off white crystalline powder
Export information
HS Code
29333990
Export Rebate
13%
UN No.
2811
DG-Class
6.1(b)
Risk Code
R60-61-25-36/37/38-43-39/23/24/25-23/24/25-11
Safety Label
T,F
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