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Jinan Jinda Pharmaceutical Chemistry Co.,Ltd.
Jinan Jinda Pharmaceutical Chemistry Co.,Ltd.
32 YRS
Shandong, China
Main Products:
Nitrofurantoin / Nitrofurantoin Monohydrate / Tolperisone Hydrochloride / Nitrofurazone / Carprofen / Dantrolene Sodium / Haloperidol / Cyclandelate / Dipyridamole / Phenylbutazone / Feprazone / Foscarnet Sodium / 1-Aminohydantoin Hydrochloride
Shandong, China
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Feprazone / CAS 30748-29-9
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Feprazone
Synonymous: 4-(b-Isoamylenyl)-1,2-diphenyl-3,5-pyrazolidinedione
CAS: 30748-29-9
Structure：
Molecular formula: C20H20N2O2
Molecular weight: 320.39
Authentication code: H37023357
Specification: National drug standard WS-10001-(HD-0432)-2002
Appearance: White or almost white crystal powder
Assay: Not less than 99.0%
Melting point: 152~157οC
Loss on Drying: Not more than 0.5%
Residue on ignition: Not more than 0.1%
Heavy metals: Not more than 10ppm
Application: It is an anti-inflammatory analgesic. Used in activity rheumatism, rheumatoid arthritis, periarthritis, infection of the upper respiratory tract, periodontium inflammation, thrombus phlebitis etc.
Typical Properties
Summary
Feprazone is a non steroidal anti-inflammatory and analgesic drug. Its anti-inflammatory, antipyretic and analgesic effects are realized by strongly inhibiting the synthesis of PG. The structural feature of feprazone is that isopentenyl with anti ulcer effect is introduced into the chemical structure, which not only retains the anti-inflammatory and analgesic effect, but also reduces the toxic and side effects, especially avoids the adverse stimulation of similar drugs on gastric mucosa.
CAS No.
30748-29-9
Formula
C20H20N2O2
Molecular Mass
320.38500
Exact Mass
320.15200
PSA
40.62000
Logp
4.08390
IUPAC
4-(3-methylbut-2-enyl)-1,2-diphenylpyrazolidine-3,5-dione
SMILES
CC(=CCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3)C
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Antipyretic Analgesics
Chemical and Physical Properties
Melting Point
156.5° (ethanol)
Density
1.174g/cm3
Boiling Point
437.2ºC at 760mmHg
Flash Point
178.7ºC
Appearance
White or off white crystalline powder
Export information
HS Code
2933990099
Export Rebate
13%
UN No.
0.0
DG-Class
0.0
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