Sulfamonomethoxine
Chinese name: 磺胺间甲氧嘧啶
CAS: 1220-83-3
Implementation criteria:CPV2010
Character：this product is white or white-like crystalline powder; Odorless, almost tasteless; Dark in light color, slightly soluble in acetone, slightly soluble in ethanol, insoluble in water, soluble in dilute hydrochloric acid or sodium hydroxide test solution.
Pharmacology：this product is a sulfa drug with strong antibacterial activity in vivo and in vitro. It has a strong inhibitory effect on most Gram-positive and negative bacteria, and the bacteria have slower resistance to this drug. SMM is mainly used for various diseases caused by sensitive bacteria, and has good curative effect on swine toxoplasmosis, swine swelling disease, avian and rabbit coccidiosis.
This product has good absorption after oral administration, high blood concentration, low acylation rate, and high solubility of ethanolates in urine, which is not easy to crystallize urine. The effective blood concentration was maintained for 24 hours for buffalo, 5.8 hours for pigs, 7 hours for goats and 2 hours for sheep.
Indications：this product is suitable for urinary tract infection, intestinal infection and skin and soft tissue infection caused by sensitive bacteria. It is also used for diarrhea, dysentery, cholera typhoid, coccidiosis, infectious pneumonia, toxoplasmosis, atrophic rhinitis, fish bacteria, etc.
Usage and Dosage：one oral dose of 1kg body weight. Livestock is 50-100mg for the first time, twice a day for 3 to 5 days.
Discontinuation period：the drug was stopped 7 days before the slaughter of chickens and pigs.
Specification：25kg/barrel
Packaging：aluminum platinum bag, cardboard barrel
Storage：keep in a closed and dry place
Validity Period：24 months
Sulfamonomethoxine is one of the most potent antimicrobials in sulfa drugs. It can be used to inhibit most Gram-positive and Gram-negative bacteria. This product also has significant effect on coccidia and Toxoplasma gondii. It can be used to treat various sensitive bacterial infections, avian coccidiosis, swine toxoplasmosis and so on. It has the strongest effect on Streptococcus, pneumococcus, Salmonella, Pasteurella, Corynebacterium pyogenes and Escherichia coli, and also has antibacterial effect on Staphylococcus, Proteus and anthrax, so it is widely used in respiratory tract, gastrointestinal tract and urinary tract infection of livestock and poultry.
IUPAC
4-amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide
SMILES
COC1=NC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N
Henan, China
