Henan, China
Henan, China
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Sulfadimethoxine / CAS 122-11-2
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Sulfadimethoxine
Introduction: sulfadiazine is a synthetic antibacterial drug widely used in clinic. The antibacterial mechanism of sulfonamides is mainly antibacterial effect, which inhibits the growth and reproduction of bacteria. For most Gram-positive bacteria, some Gram-negative bacteria are effective, but not for Rickettsia, mycoplasma, virus, etc.
CAS：122-11-2
Molecular formula: C12H14N4O4S
Molecular weight: 310.33
Structural type: 
Adverse reactions: mainly gastrointestinal reactions, teratogenic effects on renal function damage, cross allergy, etc. Sulfonamides should not be combined with local anesthetics.
Use: it is a kind of sulfonamide antibiotic that blocks the synthesis of dihydrofolate by inhibiting dihydrofolate synthase. Mode of action: inhibit folate synthesis in prokaryotes. Antibacterial spectrum: resistance mechanism of Gram-positive bacteria, Gram-negative bacteria and Chlamydia: change of dihydrofolate synthase or alternative path of folate synthesis.
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