Chloroamphenicol
English name: chloroamphenicol
CAS: 56-75-7
Formula: C11H12Cl2N2O5
Molecular weight: 323.13
Content: ≥99%
Melting point: 149℃-153℃
Specific rotation: 18.5-21.5
Residue on ignition: ≤0.1%
Heavy metal: ≤10ppm
Drying loss: ≤0.5%
Features: The product is white acicular or slight yellow-green acicular, flaky crystal or crystalline powder, is bitter in taste, easily soluble in methanol, ethanol, acetone and propylene glycol, stable in the dry state, relatively stable in faintly acid and neutral solutions and indissoluble in the boiling state, and easily fails when mixed with alkalis.
Appearance & smell: white acicular or slightly yellow-green acicular, flaky crystal or crystalline powder
Packing material: paperboard barreling.
Package specifications: The net weight of each barrel (bag) is 25kg, or packages can be provided according to user requirements.
Storage conditions: storage in shady, cool, dry and ventilated storehouses, incapability of stacking together with volatile substances.
Application: The product is an antibiotic medicine.
Chloramphenicol is a broad spectrum antibiotic introduced into clinical practice in 1948, but which was subsequently shown to cause serious and fatal aplastic anemia and is now used rarely and reserved for severe, life-threatening infections for which other antibiotics are not available. Chloramphenicol has also been linked to cases of acute, clinically apparent liver injury with jaundice, largely in association with aplastic anemia.
IUPAC
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
SMILES
C1=CC(=CC=C1[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]