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Nantong Jinghua Pharmaceutical Co.,Ltd.
Nantong Jinghua Pharmaceutical Co.,Ltd.
12 YRS
Jiangsu, China
Main Products:
Phenobarbital / Primidone###Primidone / Phenylbutazone / Fluorouracil / Flucytosine / Propylthiouracil / Piroxicam / Tenoxicam / Azelaic Acid
Jiangsu, China
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Flucytosine / CAS 2022-85-7
OVERVIEW
Uses
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
Max Capacity
210 MT/Year
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DESCRIPTION
Name of product： | 5-Fluorocytosine |
CAS No.： | 2022-85-7 |
Standard： | Ph.Eur., USP |
1.1 Legal Name: Fluorocytosine
English Name: 5-Fluorocytosine
Chemical name: 4-Amino-5-fluoro-2(1H)-pyrimidinone,5-Fc
1.2 Chemical Structural Formula
Molecular Formula:C4H4FN3O
Molecular Weight: 129.09
1.3 Physical and Chemical Properties
This product is white or off white crystalline powder. No odor or slight odor. Insoluble in ethanol, slightly soluble in chloroform and B
1.4 Approval No
Gyzz H32025152
1.5 Product Validity
three years
1.6 Role and Clinical Use
This product is an antifungal drug used to treat infections such as Candida albicans and Cryptococcus.
Typical Properties
Summary
5-fluorocytosine (5-FC), also known as 5-fluorocytosine, 5-fluorocytidine, anjezhi, and anlapen, is a white or quasi white crystalline powder. The inhibitory effect of 5-fluorocytosine on fungi is due to its entering into the cells of sensitive fungi, and under the action of cytosine deaminase, 5-fluorouracil, an anti metabolite, is formed. The latter is converted to 5-fluorouracil-2-deoxyriboside, which inhibits thymidine synthase, blocks the conversion of 5-fluorouracil-2-deoxyriboside to thymidine, and affects DNA synthesis. It has a good inhibitory effect on Candida, Cryptococcus and hyphomycetes, and also has an effect on some Aspergillus, as well as mycospores and bottle fungi which cause skin fungal diseases.
CAS No.
2022-85-7
Formula
C4H4FN3O
Molecular Mass
129.09200
Exact Mass
129.03400
PSA
71.77000
Logp
0.07240
IUPAC
6-amino-5-fluoro-1H-pyrimidin-2-one
SMILES
C1=NC(=O)NC(=C1F)N
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Synthetic Anti Infective Drugs
Chemical and Physical Properties
Melting Point
298-300 °C
Density
1.73g/cm3
Boiling Point
298ºC
Appearance
White crystalline solid
Acidity and Basicity
alkalinity reducibility
Export information
HS Code
29335990
Export Rebate
13%
Risk Code
R40-36/37/38-63
Safety Label
Xn,T,Xi
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