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Shanghai Jinhe BIO-PHARMACEUTICAL Co., Ltd.

22 YRS

Shanghai, China

CNY 3.4 Million

19980 m²

100-500 people

Main Products: Paclitaxel / Docetaxel / Docetaxel Trihydrate / Cabazitaxel / 10-Deacetylbaccatin III / Baccatine III

Shanghai, China

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Paclitaxel (Natural) USP34 / CAS 33069-62-4

OVERVIEW

Packaging

5 KG/BOTTLE

Lead Time

14-30 days

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DESCRIPTION

Paclitaxel (Natural) USP34

Product Information
Product Name	Paclitaxel (Natural) USP34
Molecular Formula	C₄₇H₅₁NO₁₄(853.9)
Cas No.	33069-62-4
Quality standard	complies with USP34
Analysis	Standard
Assay (W/W)	97.0- 102.0%
Paclitaxel (HPLC)	NLT99.5%
Physical Control
Appearance	White crystalline powder
Identification (By IR)	Complies
Identification (By HPLC)	Complies
Specific Optical Rotation	-49.0°～-55.0°
Water	NMT4.0%
Chemical Control
Residue of solvents	Complies with ICH requirement
Residue on Ignition	NMT0.2%
Bacteria Endotoxins	NMT0.4USP EU/mg
Heavy Metal	NMT20ppm
Microbial Limits	NMT100cfu/g
Impurity
Total Impurities	NMT 0.5%
Individual Impurities	NMT 0.1%
Baccatin Ⅲ	NMT0.2%
10-Deacetylpaclitaxel	NMT0.5%
7-Xylosylpaclitaxel	NMT0.2%
Cephalomannine and 2,3-Dihydrocephalomannine	NMT0.5%
10-deacetyl-7-epi-paclitaxel	NMT0.5%
Benzyl analog and 3,4-Dehydropaclitaxel C	NMT0.5%
7-Epicephalomannine	NMT0.3%
7-epi-paclitaxel	NMT0.5%
Other Individual Impurities	NMT0.1%
Storage
Store in well closed containers and perfect from light and moisture.

Typical Properties

Antineoplastic drugs. It is used to treat metastatic breast cancer and metastatic ovarian cancer. Broad-spectrum antineoplastic botanical drugs are used to treat ovarian cancer, breast cancer and other diseases.

CAS No.

33069-62-4

Formula

C47H51NO14

Molecular Mass

853.90600

Exact Mass

853.33100

PSA

221.29000

Logp

4.12660

IUPAC

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

SMILES

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C

Matter Classification

organic

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