Dihydroxycholecalciferol is vitamin 1 α， 25-d3 is one of the most important active metabolites. This metabolite is usually formed in the kidney. In recent years, it has been found that calcitriol can also be produced outside the kidney. It has been confirmed that there are 1 in placenta, monocytes, macrophages, tumor cell supernatant, lymph nodes and keratinocytes in patients with sarcoidosis α Hydroxylase can produce calcitriol. The precursor of calcitriol is 25 hydroxycholecalciferol (afacalcitol). Dihydroxycholecalciferol can promote the absorption of calcium in the small intestine and regulate the transport of inorganic salts in bone.
Manufacturing
