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Bacitracin

CAS NO.： 1405-87-4

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Specification： ≥99.5%

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Lead Time： 14-30 days

Max Capacity： -

Packing： 10KG/Fibre Drum

Product Detail

Properties

Bacitracin

1、Nomenclature

English name:Bacitracin

2、Structural formula

Molecular

Structure

杆菌肽

Molecular formula of Bacitracin A：C66H103N17O16S

Molecular weight of Bacitracin A：1422.69

CAS号CAS No.：1405-87-4

3、Mechanism and clinical use:

Bacitracin is used in medicine as a polypeptide antibiotic. Bacitracin has bactericidal action for Gram-positive bacteria & Gram-negative coccobacteria, diplococcus lanceolatus, staphylococcus, gonococcus, diplococcus intracellularis, leptospiral, etc. The mechanism of action: act on cell wall and effect protoplast, damage cellular plasma membrane and effect permeability.

It is mainly used for infection of penicillin-resistant staphylococcus, also used for skin infection, etc. Under specific concentration, it has relatively strong bactericidal action for systemic infection and topical infection. Its antibacterial spectrum is similar to penicillin G. It is often used by combination with polymyxin, neomycin.

4、Packaging size specification

Inner package: single-layer polyethylene bag and aluminum foil bag.

Outer package: fiber drum.

Packaging size: 10 Kg/drum

Properties

The product is mainly used as an animal growth promoter in feed. Due to the presence of zinc, cadmium and mercury salts, the activity of the product is enhanced, so the zinc and manganese salts of the product are often used as feed additives. Growth promoters are non nutritive additives, which can stimulate the growth of livestock and poultry, improve the rate of weight gain and feed utilization, and improve the health of livestock and poultry. It has strong antibacterial activity against most Gram-positive bacteria, similar to penicillin, and also effective against penicillin resistant Staphylococcus aureus. As a drug, it is mainly used to treat various infections caused by drug-resistant staphylococcus aureus, such as sepsis, pneumonia, endocarditis, etc.

CAS No.

1405-87-4

Formula

C66H103N17O16S

Molecular Mass

1422.69

Exact Mass

1421.75

PSA

556.17000

Logp

3.72410

IUPAC

(4S)-4-[[(2S)-2-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2R,3S)-1-[[(3R,6R,9R,12R,15R,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid

Category

Melting Point

221-225°C

Density

1.43 g/cm3

Boiling Point

1750.1ºC at 760 mmHg

Flash Point

1012.2ºC

Appearance

Light yellow to light tan powder

HS Code