Cabazitaxel

Product introduction:

Cabataxel is a microtubule inhibitor, which is suitable for the combination with prednisone or prednisolone in the treatment of patients with hormone refractory metastatic prostate cancer with docetaxel containing treatment regimen. It has achieved more accurate treatment in the whole treatment process. It acts by disrupting the microtubule network essential for mitotic and interphase cell function and causes inhibition of cell division and cell death.

CAS：183133-96-2

Molecular formula: C₄₅H₅₇NO₁₄

Molecular weight: 835.93

Character: White or off white powder, almost insoluble in water and soluble in ethanol.

Product purpose: Carbataxel combined with prednisone is used to treat hormone refractory metastatic prostate cancer previously treated with docetaxel containing regimen.

Properties

Carbataxel combined with prednisone is used to treat hormone refractory metastatic prostate cancer previously treated with docetaxel containing regimen.

CAS No.

183133-96-2

Formula

C45H57NO14

Molecular Mass

835.93200

Exact Mass

835.37800

PSA

202.45000

Logp

4.95870

IUPAC

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

Matter Classification

organic

Category

Melting Point

180 °C

Density

1.31

Boiling Point

870.7±65.0 °C(Predicted)

Appearance

White or off white powder

Acidity and Basicity