Chemical name: 9a-fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
Category: adrenocortical hormone APIs
Specifications: 1kg/tin
Standard: CP/BP/USP/EP
Approval number: Chinese Drug Approval Number H20055125
Quality standard: Chinese Pharmacopoeia 2015 edition
Properties: white or off-white crystalline powder; no odor.
Identification: positive reaction
Melting point: 236℃~244℃.
Specific rotation: +115º~+121º
Absorbance:382~406
Related substances：maximum impurity≤1.0％, other single impurities≤0.5％, total impurities≤2.0％.
Drying loss: ≤0.5%.
Residue on ignition: ≤0.1%.
Microbial limit: total amount of aerobe≤103cfu/g; mould and yeast≤102cfu/g; no escherichia coli can be detected.
Content: C22H29FO5 in dry product is 97.0%~103.0%.
Storage: the product should be tightly sealed and kept in shading place.
Chemical structural formula:
Properties
Summary
Hormone drugs. It is mainly used for anti-inflammatory and anti allergy. It is suitable for rheumatoid arthritis and various skin diseases. Betamethasone has the same effect as dexamethasone, and its anti-inflammatory effect is stronger than dexamethasone, desmoxone and hydrocortisone, and its side effects are less.
Manufacturing
